Gingival Recession

2
Pipeline Programs
2
Companies
8
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Organogenesis
OrganogenesisCANTON, MA
4 programs
1
1
GintuitPhase 31 trial
CelTxPhase 1/21 trial
CelTx™N/A1 trial
GintuitN/A1 trial
Active Trials
NCT01134081CompletedEst. Dec 2008
NCT01547962CompletedEst. May 2006
NCT00679081TerminatedEst. Sep 2010
+1 more trials
Geistlich Pharma
Geistlich PharmaSwitzerland - Root
4 programs
CAF+XCMN/A1 trial
Geistlich Fibro-GideN/A1 trial
MucograftN/A1 trial
experimental: collagen matrixN/A1 trial
Active Trials
NCT03833765Completed24Est. Jul 2017
NCT04260152Completed30Est. Jul 2020
NCT00902876Completed45Est. Jan 2012
+1 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
OrganogenesisGintuit
OrganogenesisCelTx
Geistlich PharmaGeistlich Fibro-Gide
Geistlich Pharmaexperimental: collagen matrix
Geistlich PharmaCAF+XCM
Geistlich PharmaMucograft
OrganogenesisCelTx™
OrganogenesisGintuit

Clinical Trials (8)

Total enrollment: 119 patients across 8 trials

NCT00587834OrganogenesisGintuit

Safety and Efficacy of Gintuit(TM)for Oral Soft Tissue Regeneration

Start: Oct 2007Est. completion: Dec 2008
Phase 3Completed
NCT00679081OrganogenesisCelTx

A Pilot Study of CelTx(TM) (Apligraf®) in the Treatment of Gingival Recession Requiring Root Coverage

Start: May 2008Est. completion: Sep 2010
Phase 1/2Terminated
NCT04260152Geistlich PharmaGeistlich Fibro-Gide

Evaluation of Geistlich Fibro-Gide® + CAF in Comparison to CTG + CAF for the Treatment of Recession Defects at 6 Months

Start: Sep 2018Est. completion: Jul 202030 patients
N/ACompleted
NCT03344315Geistlich Pharmaexperimental: collagen matrix

Xenogeneic Collagen Matrix or Palatal Connective Tissue Graft With a Coronally Advanced Flap in Class III Recessions

Start: Mar 2017Est. completion: Jun 202020 patients
N/ACompleted
NCT03833765Geistlich PharmaCAF+XCM

Adjunctive Benefit of a Xenogenic Collagen Matrix

Start: Nov 2012Est. completion: Jul 201724 patients
N/ACompleted
NCT00902876Geistlich PharmaMucograft

A Randomized Controlled Clinical Trial to Evaluate Safety and Effectiveness of CAF + Mucograft® Compared to CAF Alone in Patients With Gingival Recessions

Start: Mar 2009Est. completion: Jan 201245 patients
N/ACompleted
NCT01134081OrganogenesisCelTx™

Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts

Start: Jan 2008Est. completion: Dec 2008
N/ACompleted
NCT01547962OrganogenesisGintuit

A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva

Start: Sep 2005Est. completion: May 2006
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
2 companies competing in this space