Genetic Disease

2
Pipeline Programs
2
Companies
5
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

EP
Eloxx PharmaceuticalsIsrael - Nes Tziona
2 programs
1
1
ELX-02Phase 21 trial
ELX-02Phase 11 trial
Active Trials
NCT03309605CompletedEst. Jul 2019
NCT04069260TerminatedEst. Dec 2019
Genomics
GenomicsUK - Oxford
3 programs
BeginNGS TestN/A1 trial
Genetic EnrolleesN/A1 trial
Whole genome sequencingN/A1 trial
Active Trials
NCT06306521Recruiting10,000Est. Feb 2029
NCT03458962Recruiting1,000Est. Mar 2070
NCT06276348Completed120Est. Nov 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Eloxx PharmaceuticalsELX-02
Eloxx PharmaceuticalsELX-02
GenomicsBeginNGS Test
GenomicsWhole genome sequencing
GenomicsGenetic Enrollees

Clinical Trials (5)

Total enrollment: 11,120 patients across 5 trials

A Phase 2 Study of ELX-02 in Patients With Nephropathic Cystinosis

Start: Aug 2019Est. completion: Dec 2019
Phase 2Terminated

Phase 1 Study of ELX-02 in Healthy Adult Subjects

Start: Oct 2017Est. completion: Jul 2019
Phase 1Completed
NCT06306521GenomicsBeginNGS Test

An Adaptive Clinical Trial of BeginNGS Newborn Screening for Hundreds of Genetic Diseases by Genome Sequencing

Start: Feb 2024Est. completion: Feb 202910,000 patients
N/ARecruiting
NCT06276348GenomicsWhole genome sequencing

Newborn Genomic Sequencing Pilot Study

Start: Mar 2023Est. completion: Nov 2024120 patients
N/ACompleted
NCT03458962GenomicsGenetic Enrollees

Diagnostic Odyssey: Whole Genome Sequencing (WGS)

Start: Feb 2018Est. completion: Mar 20701,000 patients
N/ARecruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 11,120 patients
2 companies competing in this space