Foot Ulcer, Diabetic

4
Pipeline Programs
6
Companies
7
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
3
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Abbott
AbbottABBOTT PARK, IL
1 program
1
Medical FoodPhase 31 trial
Active Trials
NCT00711217Completed271Est. Dec 2010
Pfizer
PfizerNEW YORK, NY
2 programs
2
MRE0094Phase 21 trial
MRE0094Phase 21 trial
Active Trials
NCT00312364Completed322Est. Dec 2007
NCT00318214Terminated16Est. Feb 2008
Biotest Pharmaceuticals
Biotest PharmaceuticalsGermany - Dreieich
1 program
1
NorLeu3-APhase 21 trial
Active Trials
NCT00796744CompletedEst. May 2011
Podimetrics
PodimetricsMA - Somerville
2 programs
Daily use of podimetrics smart-foot matN/A1 trial
Once-daily remote foot temperature monitoringN/A1 trial
Active Trials
NCT02647346CompletedEst. Feb 2015
NCT04345016CompletedEst. Nov 2019
Organogenesis
OrganogenesisCANTON, MA
1 program
NuShieldN/A1 trial
Active Trials
NCT02461641CompletedEst. Oct 2018

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AbbottMedical Food
Biotest PharmaceuticalsNorLeu3-A
PfizerMRE0094
PfizerMRE0094
PodimetricsOnce-daily remote foot temperature monitoring
OrganogenesisNuShield
PodimetricsDaily use of podimetrics smart-foot mat

Clinical Trials (7)

Total enrollment: 609 patients across 7 trials

NCT00711217AbbottMedical Food

Evaluation of a Medical Food for Chronic Wounds

Start: Jun 2008Est. completion: Dec 2010271 patients
Phase 3Completed
NCT00796744Biotest PharmaceuticalsNorLeu3-A

Safety and Efficacy Study of DSC127 in Treating Subjects With Diabetic Ulcers

Start: Oct 2008Est. completion: May 2011
Phase 2Completed
NCT00318214PfizerMRE0094

Safety and Efficacy Study of MRE0094 to Treat Large, Single or Multiple, Chronic, Neuropathic, Diabetic Foot Ulcers

Start: Jun 2006Est. completion: Feb 200816 patients
Phase 2Terminated
NCT00312364PfizerMRE0094

Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers

Start: Dec 2005Est. completion: Dec 2007322 patients
Phase 2Completed
NCT04345016PodimetricsOnce-daily remote foot temperature monitoring

Impact of Remote Foot Temperature Monitoring

Start: Apr 2017Est. completion: Nov 2019
N/ACompleted
NCT02461641OrganogenesisNuShield

NuShield/Affinity for the Treatment of Neuropathic Diabetic Foot Ulcers

Start: Mar 2015Est. completion: Oct 2018
N/ACompleted
NCT02647346PodimetricsDaily use of podimetrics smart-foot mat

In-Home Assessment of a Smart Foot Mat for Prevention of Diabetic Foot Ulcers

Start: Nov 2013Est. completion: Feb 2015
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
6 companies competing in this space