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Failed Back Surgery Syndrome

2
Pipeline Programs
4
Companies
12
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Medtronic
MedtronicNJ - Phillipsburg
5 programs
1
Spinal cord stimulation with eight polar electrodePhase 41 trial
Spinal cord stimulationN/A1 trial
fMRIN/A1 trial
registration of AdaptiveStimN/A1 trial
spinal cord stimulationN/A1 trial
Active Trials
NCT05349695Unknown200Est. May 2024
NCT02650349Completed11Est. Aug 2018
NCT02974101Completed39Est. Jun 2017
+2 more trials
Boston Scientific
Boston ScientificCA - Valencia
3 programs
1
Precision Spinal Cord StimulatorPhase 41 trial
SCS implanted with Precision SpectraTMN/A1 trial
Spinal Cord StimulationN/A1 trial
Active Trials
NCT04735159Completed60Est. Jun 2019
NCT05466110Unknown84Est. May 2025
NCT01036529Terminated28Est. May 2013
Abbott
AbbottABBOTT PARK, IL
3 programs
A Post Market Study on DRG Stimulation in FBSS (SYMPATHY)N/A1 trial
Implantation with the commercially available Axium neurostimulatorN/A1 trial
SCS and PNfSN/A1 trial
Active Trials
NCT02634398Withdrawn0Est. Nov 2016
NCT02335216Terminated22Est. Jan 2017
NCT01990287Terminated38Est. Feb 2016
Nevro
NevroCA - Redwood City
1 program
fMRIN/A1 trial
Active Trials
NCT02650362Completed10Est. Aug 2018

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
MedtronicSpinal cord stimulation with eight polar electrode
Boston ScientificPrecision Spinal Cord Stimulator
Boston ScientificSpinal Cord Stimulation
MedtronicSpinal cord stimulation
Boston ScientificSCS implanted with Precision SpectraTM
Medtronicregistration of AdaptiveStim
Medtronicspinal cord stimulation
MedtronicfMRI
NevrofMRI
AbbottA Post Market Study on DRG Stimulation in FBSS (SYMPATHY)
AbbottImplantation with the commercially available Axium neurostimulator
AbbottSCS and PNfS

Clinical Trials (12)

Total enrollment: 844 patients across 12 trials

NCT01096147MedtronicSpinal cord stimulation with eight polar electrode

Efficacy Study of the Octapolar Lead in Patients With Failed Back Surgery Syndrome (FBSS) With Chronic Pain

Start: Feb 2010Est. completion: Nov 201380 patients
Phase 4Completed
NCT01036529Boston ScientificPrecision Spinal Cord Stimulator

Spinal Cord Stimulation With Precision® System Versus Reoperation for Failed Back Surgery Syndrome

Start: Feb 2010Est. completion: May 201328 patients
Phase 4Terminated
NCT05466110Boston ScientificSpinal Cord Stimulation

Spinal Cord Stimulation Versus Instrumentation for FBSS

Start: Mar 2023Est. completion: May 202584 patients
N/AUnknown
NCT05349695MedtronicSpinal cord stimulation

Patient Profiling and Outcome Assessment in Spinal Cord Stimulation for Chronic Back and/or Leg Pain

Start: May 2022Est. completion: May 2024200 patients
N/AUnknown
NCT04735159Boston ScientificSCS implanted with Precision SpectraTM

Clinical Decision Support System (CDSS) in Neurostimulation Therapy

Start: Nov 2016Est. completion: Jun 201960 patients
N/ACompleted
NCT02974101Medtronicregistration of AdaptiveStim

AdaptiveStim Objectifying Subjective Pain Questionnaires

Start: Nov 2016Est. completion: Jun 201739 patients
N/ACompleted
NCT02787265Medtronicspinal cord stimulation

High-density in Spinal Cord Stimulation: Virtual Expert Registry

Start: Jun 2016Est. completion: Dec 2020272 patients
N/ACompleted

StruCtuRal And FuncTional Brain Alterations by Conventional Spinal Cord Stimulation And High DensitY Stimulation

Start: Jan 2016Est. completion: Aug 201811 patients
N/ACompleted

STructural And FunCTional Brain Alterations by HIgh FrequenCy Spinal Cord Stimulation

Start: Jan 2016Est. completion: Aug 201810 patients
N/ACompleted
NCT02634398AbbottA Post Market Study on DRG Stimulation in FBSS (SYMPATHY)

A Post Market Study on DRG Stimulation in FBSS (SYMPATHY)

Start: Dec 2015Est. completion: Nov 20160
N/AWithdrawn
NCT02335216AbbottImplantation with the commercially available Axium neurostimulator

A Post Market Study on Dorsal Root Ganglion (DRG) Stimulation in Failed Back Surgery Syndrome (FBSS)

Start: Jan 2014Est. completion: Jan 201722 patients
N/ATerminated
NCT01990287AbbottSCS and PNfS

SENSE (Subcutaneous and Epidural Neuromodulation System Evaluation) Study

Start: Nov 2013Est. completion: Feb 201638 patients
N/ATerminated

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.