Esophagitis

4
Pipeline Programs
5
Companies
5
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
0
2
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
150%
Small Molecule
150%
+ 3 programs with unclassified modality

On Market (1)

Approved therapies currently available

U
PANTOPRAZOLE SODIUMApproved
pantoprazole
Unknown Company
oral2016

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
1 program
1
pantoprazolePhase 4Small Molecule1 trial
Active Trials
NCT00133770Completed20Est. Mar 2007
Novartis
NovartisBASEL, Switzerland
1 program
1
omalizumabPhase 2Monoclonal Antibody1 trial
Active Trials
NCT00123630Completed30Est. Jan 2010
Providence Therapeutics
1 program
1
Whole Food InterventionPhase 1/21 trial
Active Trials
NCT02575391TerminatedEst. Sep 2012
OD
1 program
Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO CapsuleN/A1 trial
Active Trials
NCT00579410CompletedEst. Oct 2009
Allergy Therapeutics
Allergy TherapeuticsUK - West Sussex
1 program
Eosinophilic Esophagitis DatabankN/A1 trial
Active Trials
NCT01323803CompletedEst. Feb 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Pfizerpantoprazole
Novartisomalizumab
Providence TherapeuticsWhole Food Intervention
Allergy TherapeuticsEosinophilic Esophagitis Databank
Ortho DevelopmentComparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule

Clinical Trials (5)

Total enrollment: 50 patients across 5 trials

NCT00133770Pfizerpantoprazole

Intravenous (IV) Pantoprazole in Erosive Esophagitis

Start: Jul 2004Est. completion: Mar 200720 patients
Phase 4Completed
NCT00123630Novartisomalizumab

A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab

Start: Nov 2005Est. completion: Jan 201030 patients
Phase 2Completed
NCT02575391Providence TherapeuticsWhole Food Intervention

The Effects of Whole Food Intervention on Mucositis in Patients Treated for Thoracic Cancer

Start: Oct 2009Est. completion: Sep 2012
Phase 1/2Terminated
NCT01323803Allergy TherapeuticsEosinophilic Esophagitis Databank

Eosinophilic Esophagitis Databank

Start: Apr 2011Est. completion: Feb 2016
N/ACompleted
NCT00579410Ortho DevelopmentComparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule

Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule

Start: May 2004Est. completion: Oct 2009
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

5 companies competing in this space