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Early Childhood Caries

2
Pipeline Programs
2
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Innovation Pharmaceuticals
2 programs
2
SDFPhase 31 trial
Sodium Fluoride VarnishPhase 31 trial
Active Trials
NCT05642494Completed220Est. Apr 2023
NCT05761041Completed140Est. Apr 2023
Frontera Therapeutics
Frontera TherapeuticsChina - Suzhou
1 program
Silver Diamine FluorideN/A1 trial
Active Trials
NCT06786975Not Yet Recruiting156Est. Feb 2027

Trial Timeline

Clinical trial activity over time

2022
2023
2024
2025
2026
2027
Innovation PharmaceuticalsSodium Fluoride Varnish
Innovation PharmaceuticalsSDF
Frontera TherapeuticsSilver Diamine Fluoride

Clinical Trials (3)

Total enrollment: 516 patients across 3 trials

NCT05761041Innovation PharmaceuticalsSodium Fluoride Varnish

Silver Diamine Fluoride Versus Sodium Fluoride Varnish With Parental Behavior Modification in Arresting Early Childhood Caries

Start: Mar 2022Est. completion: Apr 2023140 patients
Phase 3Completed
NCT05642494Innovation PharmaceuticalsSDF

Silver Diamine Fluoride(SDF) Versus SDF Combined With Sodium Fluoride Varnish in the Arrest of Early Childhood Caries

Start: Mar 2022Est. completion: Apr 2023220 patients
Phase 3Completed
NCT06786975Frontera TherapeuticsSilver Diamine Fluoride

Effectiveness and Acceptability of SDF Compared to ART for the Management of Early Childhood Caries

Start: Dec 2025Est. completion: Feb 2027156 patients
N/ANot Yet Recruiting

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.