Skip to main content

Dystonia

4
Pipeline Programs
7
Companies
13
Clinical Trials
5 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
3
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Medtronic
MedtronicNJ - Phillipsburg
5 programs
1
1
Deep brain stimulation of the internal globus pallidusPhase 41 trial
deep brain stimulationPhase 21 trial
Biphasic DBS stimulationN/A1 trial
Deep Brain Stimulation SystemN/A1 trial
Wearable Gait Sensor AnalysisN/A1 trial
Active Trials
NCT02468843Completed10Est. Aug 2016
NCT07309133Recruiting25Est. Dec 2028
NCT07323602Recruiting50Est. Dec 2029
+2 more trials
Pins Medical
Pins MedicalChina - Beijing
4 programs
1
Deep Brain StimulationPhase 41 trial
Beijing Pins Medical Co., Ltd. Deep Brain StimulatorN/A1 trial
Wearable Gait Sensor AnalysisN/A
deep brain stimulationN/A1 trial
Active Trials
NCT03017586Completed72Est. Dec 2021
NCT06480188Recruiting60Est. Mar 2026
NCT02263417Completed70Est. Jun 2020
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
2 programs
1
Deep Brain StimulationPhase 4
StimulationN/A1 trial
Active Trials
NCT02583074Unknown40Est. Dec 2018
Boston Scientific
Boston ScientificCA - Valencia
1 program
Deep Brain StimulationN/A1 trial
Active Trials
NCT02686125Recruiting300Est. Dec 2030
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
Functional Connectivity in Primary Focal DystoniaN/A1 trial
Active Trials
NCT01761903Completed60Est. Jun 2018
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
The Dystonia Coalition Natural History and Biospecimen Repository for Isolated DystoniasN/A1 trial
Active Trials
NCT01373424Completed3,265Est. Sep 2020
Vima Therapeutics
Vima TherapeuticsMA - Cambridge
1 program
VIM0423PHASE_21 trial
Active Trials
NCT07304089Recruiting100Est. May 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
Pins MedicalDeep Brain Stimulation
MedtronicDeep brain stimulation of the internal globus pallidus
Vima TherapeuticsVIM0423
Medtronicdeep brain stimulation
MedtronicDeep Brain Stimulation System
MedtronicWearable Gait Sensor Analysis
Pins Medicaldeep brain stimulation
Pins MedicalBeijing Pins Medical Co., Ltd. Deep Brain Stimulator
Boston ScientificDeep Brain Stimulation
UNION therapeuticsStimulation
MedtronicBiphasic DBS stimulation
Colorado TherapeuticsFunctional Connectivity in Primary Focal Dystonia
AbbVieThe Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias

Clinical Trials (13)

Total enrollment: 4,116 patients across 13 trials

NCT02263417Pins MedicalDeep Brain Stimulation

A Randomized Controlled Trail Comparing Subthalamic and Pallidal Deep Brain Stimulation for Dystonia

Start: Jul 2015Est. completion: Jun 202070 patients
Phase 4Completed
NCT00142259MedtronicDeep brain stimulation of the internal globus pallidus

Efficacy and Safety of DBS of the GPi in Patients With Primary Generalized and Segmental Dystonia

Start: Oct 2002Est. completion: Aug 200940 patients
Phase 4Unknown
NCT07304089Vima TherapeuticsVIM0423

A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

Start: Feb 2026Est. completion: May 2027100 patients
Phase 2Recruiting
NCT00331669Medtronicdeep brain stimulation

Efficacy and Safety of Deep Brain Stimulation (DBS) of the Pallidal (GPi) in Patients With Tardive Dystonia

Start: May 2006Est. completion: Dec 201024 patients
Phase 2Unknown
NCT07309133MedtronicDeep Brain Stimulation System

Local Field Potentials in Dystonia

Start: Sep 2025Est. completion: Dec 202825 patients
N/ARecruiting
NCT07323602MedtronicWearable Gait Sensor Analysis

Predicting DBS Outcomes in Dystonia Using Wearable Gait Sensors

Start: Aug 2025Est. completion: Dec 202950 patients
N/ARecruiting
NCT06480188Pins Medicaldeep brain stimulation

Differences in Brain Network Mechanisms Between STN and GPi Deep Brain Stimulation in the Treatment of Craniocervical Dystonia

Start: Mar 2024Est. completion: Mar 202660 patients
N/ARecruiting
NCT03017586Pins MedicalBeijing Pins Medical Co., Ltd. Deep Brain Stimulator

Efficacy and Safety of DBS in Patients With Primary Dystonia

Start: Dec 2017Est. completion: Dec 202172 patients
N/ACompleted
NCT02686125Boston ScientificDeep Brain Stimulation

Vercise™ DBS Dystonia Prospective Study

Start: Mar 2016Est. completion: Dec 2030300 patients
N/ARecruiting
NCT02583074UNION therapeuticsStimulation

Clinical Trial of STN-DBS for Primary Cranial-Cervical Dystonia

Start: Sep 2015Est. completion: Dec 201840 patients
N/AUnknown
NCT02468843MedtronicBiphasic DBS stimulation

Novel Stimulation Patterns for the Treatment of Dystonia

Start: Jul 2015Est. completion: Aug 201610 patients
N/ACompleted
NCT01761903Colorado TherapeuticsFunctional Connectivity in Primary Focal Dystonia

Functional Connectivity in Primary Focal Dystonia

Start: May 2012Est. completion: Jun 201860 patients
N/ACompleted
NCT01373424AbbVieThe Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias

The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias

Start: Jan 2011Est. completion: Sep 20203,265 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

5 actively recruiting trials targeting 4,116 patients
7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.