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Developmental and Epileptic Encephalopathy

2
Pipeline Programs
4
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
2
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Gene Therapy
2100%
+ 1 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

BioTherapeutics Inc
BioTherapeutics IncVA - Blacksburg
1 program
1
gene therapyPhase 1/2Gene Therapy1 trial
Active Trials
NCT06983158Suspended12Est. Dec 2028
Capsida Biotherapeutics
Capsida BiotherapeuticsCA - Thousand Oaks
1 program
1
gene therapyPhase 1/2Gene Therapy
Biocorp
BiocorpFrance - Issoire
1 program
Long-read Whole Genome SequencingN/A1 trial
Active Trials
NCT07396883Not Yet Recruiting20Est. Jun 2028

Trial Timeline

Clinical trial activity over time

2025
2026
2027
2028
BioTherapeutics Incgene therapy
BiocorpLong-read Whole Genome Sequencing

Clinical Trials (2)

Total enrollment: 32 patients across 2 trials

A Clinical Trial of CAP-002 Gene Therapy in Pediatric Patients With Syntaxin-Binding Protein 1 (STXBP1) Encephalopathy

Start: Jul 2025Est. completion: Dec 202812 patients
Phase 1/2Suspended
NCT07396883BiocorpLong-read Whole Genome Sequencing

Developmental and Epileptic Encephalopathies Diagnosed Via Long-read Genome Sequencing

Start: Jun 2026Est. completion: Jun 202820 patients
N/ANot Yet Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

Gene Therapy is the dominant modality (100% of programs)
4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.