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Denture Retention

3
Pipeline Programs
3
Companies
8
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

ViiV Healthcare
ViiV HealthcareNC - Durham
7 programs
2
1
Marketed Denture AdhesivePhase 4
Experimental Denture AdhesivePhase 3
Investigational denture adhesive creamPhase 3
Denture Adhesive CreamN/A
Experimental Denture AdhesiveN/A
+2 more programs
GSK
GSKLONDON, United Kingdom
7 programs
Denture Adhesive CreamN/A1 trial
Experimental Denture AdhesiveN/A1 trial
Test ProductN/A1 trial
Test Product 1N/A1 trial
Experimental Denture AdhesivePHASE_31 trial
+2 more programs
Active Trials
NCT03345108Completed48Est. Dec 2017
NCT02928380Completed83Est. Sep 2016
NCT03037307Completed44Est. May 2017
+4 more trials
MTI
MTIUT - Salt Lake City
1 program
PEEK clipN/A1 trial
Active Trials
NCT06866067Completed12Est. Sep 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
GSKMarketed Denture Adhesive
GSKInvestigational denture adhesive cream
GSKExperimental Denture Adhesive
MTIPEEK clip
GSKDenture Adhesive Cream
GSKTest Product 1
GSKTest Product
GSKExperimental Denture Adhesive

Clinical Trials (8)

Total enrollment: 380 patients across 8 trials

NCT03709810GSKMarketed Denture Adhesive

A Study to Investigate Food Occlusion Efficacy of a Denture Adhesive in Denture Wearers

Start: Jan 2019Est. completion: Jan 201949 patients
Phase 4Completed
NCT04473521GSKInvestigational denture adhesive cream

A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive

Start: Oct 2020Est. completion: Jan 20210
Phase 3Withdrawn
NCT03807700GSKExperimental Denture Adhesive

To Evaluate Oral Health and Quality of Life Associated With Use of a Denture Adhesive

Start: Feb 2019Est. completion: May 2019119 patients
Phase 3Completed

The Effect of Clip Material on the Retention of Implant Supported Mandibular Overdenture

Start: Feb 2024Est. completion: Sep 202412 patients
N/ACompleted
NCT03345108GSKDenture Adhesive Cream

A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers

Start: Nov 2017Est. completion: Dec 201748 patients
N/ACompleted
NCT02937870GSKTest Product 1

A Bite Force Study Comparing Two New Test Adhesives With Currently Marketed Denture Adhesive

Start: Mar 2017Est. completion: Apr 201725 patients
N/ACompleted
NCT03037307GSKTest Product

A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive

Start: Feb 2017Est. completion: May 201744 patients
N/ACompleted
NCT02928380GSKExperimental Denture Adhesive

Evaluation of a Experimental Denture Adhesive to Prevent Food Ingress

Start: Jul 2016Est. completion: Sep 201683 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.