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Dental Plaque

2
Pipeline Programs
4
Companies
7
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

ViiV Healthcare
ViiV HealthcareNC - Durham
5 programs
1
Reference MTBPhase 2
20% w/w sodium bicarbonateN/A
67% Sodium Bicarbonate with 6 herbs plus 923parts per millionN/A
Oral B Indicator 123N/A
Test zinc-IPMP toothpasteN/A
Pfizer
PfizerNEW YORK, NY
1 program
1
Negative ControlPhase 11 trial
Active Trials
NCT00762151Completed18Est. Jan 2008
GSK
GSKLONDON, United Kingdom
5 programs
20% w/w sodium bicarbonateN/A1 trial
67% Sodium Bicarbonate with 6 herbs plus 923parts per millionN/A1 trial
Oral B Indicator 123N/A1 trial
Test zinc-IPMP toothpasteN/A1 trial
Reference MTBPHASE_21 trial
Active Trials
NCT02992691Completed75Est. Feb 2017
NCT03285984Completed56Est. May 2012
NCT04025684Completed80Est. Dec 2019
+2 more trials
Philips
PhilipsNetherlands - Amsterdam
1 program
Manual ToothbrushN/A1 trial
Active Trials
NCT01250769Completed170Est. Jun 2010

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
GSKReference MTB
PfizerNegative Control
GSKOral B Indicator 123
GSK20% w/w sodium bicarbonate
GSKTest zinc-IPMP toothpaste
GSK67% Sodium Bicarbonate with 6 herbs plus 923parts per million
PhilipsManual Toothbrush

Clinical Trials (7)

Total enrollment: 484 patients across 7 trials

NCT03809910GSKReference MTB

Dental Plaque Removal Ability of Prototype Power Toothbrush Versus a Manual Toothbrush in Healthy Participants

Start: Jul 2019Est. completion: Aug 201940 patients
Phase 2Completed
NCT00762151PfizerNegative Control

A Study to Investigate the Anti-Plaque Effect of AN0128 Toothpaste

Start: Nov 2007Est. completion: Jan 200818 patients
Phase 1Completed
NCT04025684GSKOral B Indicator 123

Efficacy of Manual Toothbrushes in Removing Dental Plaque

Start: Sep 2019Est. completion: Dec 201980 patients
N/ACompleted
NCT02992691GSK20% w/w sodium bicarbonate

Efficacy of Three Experimental Toothpastes to Remove Plaque

Start: Dec 2016Est. completion: Feb 201775 patients
N/ACompleted
NCT02856880GSKTest zinc-IPMP toothpaste

A Study to Investigate the Antimicrobial Activity of 2 Test Toothpastes

Start: Nov 2015Est. completion: Dec 201545 patients
N/ACompleted
NCT03285984GSK67% Sodium Bicarbonate with 6 herbs plus 923parts per million

Ability of Four Toothpastes to Remove Plaque

Start: Mar 2012Est. completion: May 201256 patients
N/ACompleted
NCT01250769PhilipsManual Toothbrush

Evaluating the Effect of Tooth Cleaning Devices on Oral Health

Start: Apr 2010Est. completion: Jun 2010170 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.