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Dental Plaque

2
Pipeline Programs
4
Companies
8
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

ViiV Healthcare
ViiV HealthcareNC - Durham
5 programs
1
Reference MTBPhase 21 trial
20% w/w sodium bicarbonateN/A1 trial
67% Sodium Bicarbonate with 6 herbs plus 923parts per millionN/A1 trial
Oral B Indicator 123N/A1 trial
Test zinc-IPMP toothpasteN/A1 trial
Active Trials
NCT02992691Completed75Est. Feb 2017
NCT03285984Completed56Est. May 2012
NCT04025684Completed80Est. Dec 2019
+2 more trials
Pfizer
PfizerNEW YORK, NY
1 program
1
Negative ControlPhase 11 trial
Active Trials
NCT00762151Completed18Est. Jan 2008
GSK
GSKLONDON, United Kingdom
5 programs
20% w/w sodium bicarbonateN/A
67% Sodium Bicarbonate with 6 herbs plus 923parts per millionN/A
Oral B Indicator 123N/A
Test zinc-IPMP toothpasteN/A
Reference MTBPHASE_2
Philips
PhilipsNetherlands - Amsterdam
1 program
Manual ToothbrushN/A2 trials
Active Trials
NCT07691814Completed104Est. Nov 2020
NCT01250769Completed170Est. Jun 2010

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
ViiV HealthcareReference MTB
PfizerNegative Control
PhilipsManual Toothbrush
ViiV HealthcareOral B Indicator 123
ViiV Healthcare20% w/w sodium bicarbonate
ViiV HealthcareTest zinc-IPMP toothpaste
ViiV Healthcare67% Sodium Bicarbonate with 6 herbs plus 923parts per million
PhilipsManual Toothbrush

Clinical Trials (8)

Total enrollment: 588 patients across 8 trials

NCT03809910ViiV HealthcareReference MTB

Dental Plaque Removal Ability of Prototype Power Toothbrush Versus a Manual Toothbrush in Healthy Participants

Start: Jul 2019Est. completion: Aug 201940 patients
Phase 2Completed
NCT00762151PfizerNegative Control

A Study to Investigate the Anti-Plaque Effect of AN0128 Toothpaste

Start: Nov 2007Est. completion: Jan 200818 patients
Phase 1Completed
NCT07691814PhilipsManual Toothbrush

Powered Toothbrush Versus Manual Toothbrush on Plaque and Gingivitis After a Six-Week Period of Home Use

Start: Oct 2020Est. completion: Nov 2020104 patients
N/ACompleted
NCT04025684ViiV HealthcareOral B Indicator 123

Efficacy of Manual Toothbrushes in Removing Dental Plaque

Start: Sep 2019Est. completion: Dec 201980 patients
N/ACompleted
NCT02992691ViiV Healthcare20% w/w sodium bicarbonate

Efficacy of Three Experimental Toothpastes to Remove Plaque

Start: Dec 2016Est. completion: Feb 201775 patients
N/ACompleted
NCT02856880ViiV HealthcareTest zinc-IPMP toothpaste

A Study to Investigate the Antimicrobial Activity of 2 Test Toothpastes

Start: Nov 2015Est. completion: Dec 201545 patients
N/ACompleted
NCT03285984ViiV Healthcare67% Sodium Bicarbonate with 6 herbs plus 923parts per million

Ability of Four Toothpastes to Remove Plaque

Start: Mar 2012Est. completion: May 201256 patients
N/ACompleted
NCT01250769PhilipsManual Toothbrush

Evaluating the Effect of Tooth Cleaning Devices on Oral Health

Start: Apr 2010Est. completion: Jun 2010170 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.