Dental Pain
4
Pipeline Programs
3
Companies
4
Clinical Trials
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
2
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
3 companies ranked by most advanced pipeline stage
IBSA Institut BiochimiqueSwitzerland - Lugano-Pazzallo
2 programs2
Diclofenac HPBCDPhase 31 trial
Diclofenac HPBCD s.c. 75mg/mlPhase 31 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
IBSA Institut BiochimiqueDiclofenac HPBCD s.c. 75mg/ml
IBSA Institut BiochimiqueDiclofenac HPBCD
Xenon PharmaceuticalsXPF-001
AlkermesN1539
Clinical Trials (4)
Total enrollment: 61 patients across 4 trials
Evaluation of the Efficacy and Safety of Diclofenac HPBCD 75mg/ml in Treatment of Pain Following Dental Surgery
Start: Sep 2009Est. completion: May 2010
Phase 3Completed
Evaluation of the Efficacy and Safety of Diclofenac HPBCD 25, 50 mg/ml in the Treatment of Post-surgical Pain Following Dental Surgery
Start: Sep 2009Est. completion: Apr 2010
Phase 3Completed
Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction
Start: Sep 2009Est. completion: Dec 200961 patients
Phase 2Completed
Single Dose Study of N1539 in the Treatment of Pain Secondary to Dental Impaction Surgery
Start: Jul 2009Est. completion: Nov 2009
Phase 2Completed
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
2 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space