Delirium

2
Pipeline Programs
6
Companies
6
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Providence Therapeutics
1 program
1
Dexmedetomidine Hydrochloride GroupPhase 41 trial
Active Trials
NCT04289142RecruitingEst. Mar 2029
Novartis
NovartisBASEL, Switzerland
1 program
1
Rivastigmine prevention of deliriumPhase 31 trial
Active Trials
NCT00257868Completed120Est. Jul 2007
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
BIS guidance of anesthesiaN/A1 trial
Active Trials
NCT05656703Completed130Est. Mar 2021
Abbott
AbbottABBOTT PARK, IL
1 program
DexmedetomidineN/A1 trial
Active Trials
NCT00417664Completed90Est. Apr 2004
Ceribell
CeribellCA - Sunnyvale
1 program
ElectroencephalogramN/A1 trial
Active Trials
NCT04962815Recruiting200Est. Apr 2026
Hamilton medical
Hamilton medicalSwitzerland - Bonaduz
1 program
The Delirium-CS Canada StudyN/A1 trial
Active Trials
NCT02206880CompletedEst. Jul 2018

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
Providence TherapeuticsDexmedetomidine Hydrochloride Group
NovartisRivastigmine prevention of delirium
CeribellElectroencephalogram
Heidelberg PharmaBIS guidance of anesthesia
Hamilton medicalThe Delirium-CS Canada Study
AbbottDexmedetomidine

Clinical Trials (6)

Total enrollment: 540 patients across 6 trials

NCT04289142Providence TherapeuticsDexmedetomidine Hydrochloride Group

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Start: Dec 2019Est. completion: Mar 2029
Phase 4Recruiting
NCT00257868NovartisRivastigmine prevention of delirium

Rivastigmine for the Prevention of Postoperative Delirium in Patients Undergoing Cardiac Surgery

Start: Jan 2006Est. completion: Jul 2007120 patients
Phase 3Completed
NCT04962815CeribellElectroencephalogram

Ceribell Delirium Data Collection Study

Start: Nov 2021Est. completion: Apr 2026200 patients
N/ARecruiting
NCT05656703Heidelberg PharmaBIS guidance of anesthesia

Anesthesia Depth Increases Delirium Incidence

Start: Sep 2015Est. completion: Mar 2021130 patients
N/ACompleted
NCT02206880Hamilton medicalThe Delirium-CS Canada Study

The Delirium-CS Canada Study

Start: Nov 2014Est. completion: Jul 2018
N/ACompleted
NCT00417664AbbottDexmedetomidine

Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients

Start: Apr 2002Est. completion: Apr 200490 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
2 actively recruiting trials targeting 540 patients
6 companies competing in this space