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Degeneration of Lumbar Intervertebral Disc

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Pipeline Programs
5
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Zimmer Biomet
Zimmer BiometFL - Jacksonville
1 program
Aspen Spinous Process Fixation DeviceN/A1 trial
Active Trials
NCT01549366Completed64Est. Jan 2016
Globus Medical
Globus MedicalAUDUBON, PA
1 program
Multimodality Neuromonitoring in XLIFN/A1 trial
Active Trials
NCT01499680Completed323Est. Jun 2014
NuVasive
NuVasiveCA - San Diego
1 program
Multimodality Neuromonitoring in XLIFN/A
Spineology
SpineologyMN - St. Paul
1 program
Structural Allograft SpacerN/A1 trial
Active Trials
NCT00764491Completed156Est. May 2013
Medtronic
MedtronicNJ - Phillipsburg
1 program
rhBMP-2/ACS/LT-CAGE® DeviceN/A1 trial
Active Trials
NCT01491373Completed14Est. Sep 1999

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Zimmer BiometAspen Spinous Process Fixation Device
Globus MedicalMultimodality Neuromonitoring in XLIF
SpineologyStructural Allograft Spacer
MedtronicrhBMP-2/ACS/LT-CAGE® Device

Clinical Trials (4)

Total enrollment: 557 patients across 4 trials

NCT01549366Zimmer BiometAspen Spinous Process Fixation Device

Comparison of the Aspen Device Versus Pedicle Screws for Supplemental Posterior Fixation in Lumbar Interbody Fusion

Start: Feb 2012Est. completion: Jan 201664 patients
N/ACompleted
NCT01499680Globus MedicalMultimodality Neuromonitoring in XLIF

Multimodality Neuromonitoring in XLIF

Start: Oct 2011Est. completion: Jun 2014323 patients
N/ACompleted
NCT00764491SpineologyStructural Allograft Spacer

OptiMesh® for Lumbar Interbody Fusion Trial (OLIF)

Start: Jul 2003Est. completion: May 2013156 patients
N/ACompleted
NCT01491373MedtronicrhBMP-2/ACS/LT-CAGE® Device

Pilot Study of rhBMP-2/ACS/LT-CAGE® for Anterior Lumbar Interbody Fusion in Patients With Degenerative Disc Disease

Start: Jan 1997Est. completion: Sep 199914 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.