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Critically Ill

2
Pipeline Programs
7
Companies
6
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

7 companies ranked by most advanced pipeline stage

UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
1
Remimazolam BesylatePhase 21 trial
Active Trials
NCT05539521Unknown60Est. Mar 2023
Bactiguard
BactiguardSweden - Tullinge
1 program
1
Coated devicesPhase 1/21 trial
Active Trials
NCT03868241Completed103Est. Feb 2020
Baxter
BaxterCosta Rica - Cartago
1 program
Critically ill patients with continuous renal replacement therapyN/A
Baxter International
1 program
Critically ill patients with continuous renal replacement therapyN/A1 trial
Active Trials
NCT05450185Recruiting600Est. Aug 2025
Medtronic
MedtronicNJ - Phillipsburg
1 program
PSV ventilation strategyN/A1 trial
Active Trials
NCT02447692Completed575Est. Jul 2024
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
T-line hemodynamic monitoring deviceN/A1 trial
Active Trials
NCT01311128Terminated31Est. Dec 2014
Innovation Pharmaceuticals
1 program
Tailored Change StrategyN/A1 trial
Active Trials
NCT01168128Completed278Est. Sep 2011

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
UNION therapeuticsRemimazolam Besylate
BactiguardCoated devices
Baxter InternationalCritically ill patients with continuous renal replacement therapy
MedtronicPSV ventilation strategy
Oregon TherapeuticsT-line hemodynamic monitoring device
Innovation PharmaceuticalsTailored Change Strategy

Clinical Trials (6)

Total enrollment: 1,647 patients across 6 trials

NCT05539521UNION therapeuticsRemimazolam Besylate

Efficacy and Safety of Remimazolam Besylate Versus Propofol for Sedation in Critically Ill Patients With Deep Sedation

Start: Sep 2022Est. completion: Mar 202360 patients
Phase 2Unknown
NCT03868241BactiguardCoated devices

Coated Devices to Decrease Infection in the Intensive Care Unit

Start: Apr 2019Est. completion: Feb 2020103 patients
Phase 1/2Completed
NCT05450185Baxter InternationalCritically ill patients with continuous renal replacement therapy

Filter Lifespan in Continuous Renal Replacement Therapy

Start: Mar 2023Est. completion: Aug 2025600 patients
N/ARecruiting
NCT02447692MedtronicPSV ventilation strategy

Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study

Start: Sep 2016Est. completion: Jul 2024575 patients
N/ACompleted
NCT01311128Oregon TherapeuticsT-line hemodynamic monitoring device

Determination of the Accuracy of a Non-Invasive Continuous Blood Pressure Device

Start: Feb 2011Est. completion: Dec 201431 patients
N/ATerminated
NCT01168128Innovation PharmaceuticalsTailored Change Strategy

PERFormance Enhancement of the Canadian Nutrition Guidelines by a Tailored Implementation Strategy: The PERFECTIS Study

Start: Sep 2009Est. completion: Sep 2011278 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 1,647 patients
7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.