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Contact Lens Care

2
Pipeline Programs
1
Companies
21
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

1 companies ranked by most advanced pipeline stage

Alcon
AlconFORT WORTH, TX
8 programs
2
AOSEPT PlusPhase 41 trial
OPTI-FREEPhase 45 trials
FID 107027 Multi-Purpose Disinfecting SolutionN/A1 trial
Hydrogen peroxide-based contact lens care systemN/A1 trial
Multi-purpose solutionsN/A1 trial
+3 more programs
Active Trials
NCT00382681Completed252Est. Nov 2004
NCT01494818Completed79Est. Jul 2012
NCT00407238Completed25Est. Mar 2007
+9 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AlconOPTI-FREE
AlconAOSEPT Plus
AlconOPTI-FREE
AlconOPTI-FREE
AlconOPTI-FREE
AlconOPTI-FREE
AlconHydrogen peroxide-based contact lens care system
AlconOPTI-FREE
AlconOPTI-FREE
AlconOPTI-FREE
AlconOPTI-FREE
AlconOPTI-FREE
AlconOPTI-FREE
AlconOPTI-FREE
AlconOPTI-FREE

Showing 15 of 21 trials with date data

Clinical Trials (21)

Total enrollment: 2,254 patients across 21 trials

NCT01250925AlconOPTI-FREE

Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface

Start: Aug 2010Est. completion: Jul 201294 patients
Phase 4Completed
NCT06588400AlconAOSEPT Plus

AOSEPT (CLEAR CARE) PLUS Study

Start: Oct 2025Est. completion: Jan 20260
N/AWithdrawn
NCT06592521AlconOPTI-FREE

OPTI-FREE Family STUDY

Start: Oct 2025Est. completion: Jan 20260
N/AWithdrawn
NCT04702984AlconOPTI-FREE

Clinical Characterization of an Investigational Frequent Replacement Daily Wear Silicone Hydrogel Sphere Contact Lens

Start: Jan 2021Est. completion: Feb 202139 patients
N/ACompleted
NCT02251561AlconOPTI-FREE

Clinical Evaluation of Opti-Free III (FID 109182) Compared to Opti-Free Plus® in Japan

Start: Nov 2013Est. completion: May 201436 patients
N/ACompleted
NCT01809197AlconOPTI-FREE

Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution

Start: Apr 2013Est. completion: Jul 2013387 patients
N/ACompleted
NCT01494818AlconHydrogen peroxide-based contact lens care system

Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues

Start: Nov 2011Est. completion: Jul 201279 patients
N/ACompleted
NCT01476722AlconOPTI-FREE

Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)

Start: Jun 2011Est. completion: Oct 2011125 patients
N/ACompleted
NCT00724269AlconOPTI-FREE

Comparison of OPTI-FREE RepleniSH and ReNu Multi-Plus Lens Care Regimens on Corneal Epithelium

Start: Oct 2009Est. completion: Jul 201120 patients
N/ACompleted
NCT00995189AlconOPTI-FREE

Clinical Evaluation of the Causes of Contact Lens Related Dry Eye

Start: Aug 2009Est. completion: Apr 2010159 patients
N/ACompleted
NCT00982046AlconOPTI-FREE

A Clinical Comparison of Three Contact Lens Care Systems and Their Effect on Contact Lenses

Start: Apr 2009Est. completion: May 201075 patients
N/ACompleted
NCT00804999AlconOPTI-FREE

Two Phase Clinical Study of the Impact of Contact Lenses and Solutions on Corneal Structure

Start: Nov 2008Est. completion: Mar 200951 patients
N/ACompleted
NCT00772707AlconOPTI-FREE

A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)

Start: Sep 2008Est. completion: Oct 2008114 patients
N/ACompleted
NCT00789529AlconOPTI-FREE

Objective Testing of Tear Film Stability

Start: Sep 2008Est. completion: Nov 200832 patients
N/ACompleted
NCT00691457AlconOPTI-FREE

Comparison of 3 Novel Contact Lens Solutions on the Basal Lamina

Start: Apr 2008Est. completion: Jan 200915 patients
N/ACompleted
NCT00754338AlconOPTI-FREE

Evaluation of Disinfecting Solutions and Protein Remover With a Silicone Hydrogel Lens

Start: Jan 2008Est. completion: Sep 200876 patients
N/ACompleted
NCT00407238AlconMulti-purpose solutions

Corneal Barrier Function With Multi-Purpose Solutions

Start: Nov 2006Est. completion: Mar 200725 patients
N/ACompleted
NCT00383201AlconOptiFree Multi-Purpose Disinfecting Solution

Effect of Multi-Purpose Solutions on Ex-Vivo Wetting Angles

Start: Mar 2005Est. completion: Sep 200580 patients
N/ACompleted
NCT00382603AlconOptiFree Multi-Purpose Disinfecting Solution

Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Soft Contact Lenses in Symptomatic Patients

Start: Aug 2004Est. completion: Feb 2005362 patients
N/ACompleted
NCT00382902AlconOptiFree Multi-Purpose Disinfecting Solution

Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Silicone Hydrogel Soft Contact Lenses

Start: Aug 2004Est. completion: Feb 2005233 patients
N/ACompleted
NCT00382681AlconFID 107027 Multi-Purpose Disinfecting Solution

Evaluation of an Investigational Multi-Purpose Disinfecting Solution for Care of Soft Contact Lenses

Start: Jul 2004Est. completion: Nov 2004252 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.