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Concussion, Brain

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Pipeline Programs
6
Companies
8
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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0
0
0
0
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Oculogica
OculogicaWI - New Richmond
3 programs
EyeBOX LensN/A1 trial
EyeBOX Model EBX-4N/A1 trial
EyeBOX deviceN/A1 trial
Active Trials
NCT05527041Enrolling By Invitation1,600Est. Sep 2025
NCT05047003Completed100Est. Oct 2022
NCT03966404Completed200Est. Jun 2023
Human BioSciences
Human BioSciencesWV - Martinsburg
2 programs
Concussion-focused cognitive behavioral therapyN/A1 trial
MSTEPN/A1 trial
Active Trials
NCT06036147Recruiting304Est. Jan 2028
NCT04688255Active Not Recruiting200Est. Oct 2025
T-Therapeutics
T-TherapeuticsUK - Cambridge
1 program
Osteopathic Manipulative TherapyN/A1 trial
Active Trials
NCT04063618TerminatedEst. Nov 2021
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
Pre-game Safety HuddlesN/A1 trial
Active Trials
NCT04099329Completed500Est. Mar 2020
Medtronic
MedtronicNJ - Phillipsburg
1 program
The Role of Cerebral Oximetry in Pediatric Concussion AssessmentN/A1 trial
Active Trials
NCT02036333Terminated59Est. Jun 2015

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Human BioSciencesConcussion-focused cognitive behavioral therapy
OculogicaEyeBOX Lens
Human BioSciencesMSTEP
OculogicaEyeBOX Model EBX-4
T-TherapeuticsOsteopathic Manipulative Therapy
Oregon TherapeuticsPre-game Safety Huddles
OculogicaEyeBOX device
MedtronicThe Role of Cerebral Oximetry in Pediatric Concussion Assessment

Clinical Trials (8)

Total enrollment: 2,963 patients across 8 trials

NCT06036147Human BioSciencesConcussion-focused cognitive behavioral therapy

Concussion Health Improvement Program

Start: Nov 2023Est. completion: Jan 2028304 patients
N/ARecruiting
NCT05527041OculogicaEyeBOX Lens

A Highly Portable Device for Assessment of Mild Traumatic Brain Injury in Deployed and Far-Forward Settings

Start: Jul 2023Est. completion: Sep 20251,600 patients
N/AEnrolling By Invitation
NCT04688255Human BioSciencesMSTEP

Mobile Subthreshold Exercise Program for Concussion--R01

Start: Mar 2021Est. completion: Oct 2025200 patients
N/AActive Not Recruiting
NCT05047003OculogicaEyeBOX Model EBX-4

Oculogica Portable EyeBOX Study

Start: Dec 2020Est. completion: Oct 2022100 patients
N/ACompleted
NCT04063618T-TherapeuticsOsteopathic Manipulative Therapy

Reduction of Concussion Symptoms Through the Use of Osteopathic Manipulative Therapy

Start: Dec 2019Est. completion: Nov 2021
N/ATerminated
NCT04099329Oregon TherapeuticsPre-game Safety Huddles

One Team: Changing the Culture of Youth Sport With Pregame Safety Huddles

Start: Aug 2019Est. completion: Mar 2020500 patients
N/ACompleted
NCT03966404OculogicaEyeBOX device

EyeBOX Concussion Study and Registry

Start: Aug 2019Est. completion: Jun 2023200 patients
N/ACompleted
NCT02036333MedtronicThe Role of Cerebral Oximetry in Pediatric Concussion Assessment

The Role of Cerebral Oximetry in Pediatric Concussion Assessment

Start: Jan 2014Est. completion: Jun 201559 patients
N/ATerminated

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 2,963 patients
6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.