Skip to main content

Colorectal Surgery

4
Pipeline Programs
5
Companies
5
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
4
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

MSD
MSDIreland - Ballydine
2 programs
2
AlvimopanPhase 3
MK0826, ertapenem sodiumPhase 3
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
2 programs
2
AlvimopanPhase 31 trial
MK0826, ertapenem sodiumPhase 31 trial
Active Trials
NCT02742181Terminated14Est. Jul 2018
NCT00090272Completed952Est. Mar 2005
Prescient Therapeutics
Prescient TherapeuticsAustralia - South Melbourne
1 program
CleanCision Wound Retraction and Protection SystemN/A1 trial
Active Trials
NCT03816995Completed702Est. Aug 2023
Edwards Lifesciences
1 program
ERAS perioperative careN/A1 trial
Active Trials
NCT03189550Completed664Est. Feb 2017
Exero Medical
Exero MedicalIsrael - Or Yehuda
1 program
xBar systemN/A1 trial
Active Trials
NCT06168669Recruiting190Est. Dec 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Sharp TherapeuticsAlvimopan
Sharp TherapeuticsMK0826, ertapenem sodium
Exero MedicalxBar system
Prescient TherapeuticsCleanCision Wound Retraction and Protection System
Edwards LifesciencesERAS perioperative care

Clinical Trials (5)

Total enrollment: 2,522 patients across 5 trials

NCT02742181Sharp TherapeuticsAlvimopan

Alvimopan as Rescue in Post op Ileus

Start: Dec 2015Est. completion: Jul 201814 patients
Phase 3Terminated
NCT00090272Sharp TherapeuticsMK0826, ertapenem sodium

A Single Dose of a Marketed Drug Being Studied for a New Indication to Treat Surgical Site Infection Following Colorectal Surgery as Compared to a Marketed Drug Approved for This Indication (0826-039)

Start: Apr 2002Est. completion: Mar 2005952 patients
Phase 3Completed
NCT06168669Exero MedicalxBar system

A Safety and Effectiveness Prospective Blinded Clinical Study to Validate xBar System as Monitoring Tool for Anastomotic Leaks Detection

Start: Mar 2023Est. completion: Dec 2025190 patients
N/ARecruiting
NCT03816995Prescient TherapeuticsCleanCision Wound Retraction and Protection System

Prospective, Randomized, Parallel-arm Clinical Trial of CleanCision or Alexis O in Elective Colorectal Surgery

Start: Feb 2019Est. completion: Aug 2023702 patients
N/ACompleted
NCT03189550Edwards LifesciencesERAS perioperative care

Enhanced Recovery After Surgery in Colorectal Surgery: A Large-Scale Quality Improvement Project

Start: Jul 2014Est. completion: Feb 2017664 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 late-stage (Phase 3) programs, potential near-term approvals
1 actively recruiting trials targeting 2,522 patients
5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.