Cocaine Use Disorder

3
Pipeline Programs
2
Companies
5
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Soterix Medical
Soterix MedicalNJ - Woodbridge
3 programs
1
transcranial direct current stimulatorPhase 21 trial
Soterix Medical mini-CT tDCS stimulatorN/A1 trial
Transcranial Direct Current StimulatorN/A1 trial
Active Trials
NCT03833583CompletedEst. Sep 2019
NCT07318480RecruitingEst. Feb 2030
NCT04994821CompletedEst. Sep 2022
Tempero Bio
Tempero BioCA - Oakland
2 programs
2
Cohort 1 - TMP-301Phase 11 trial
TMP-301Phase 11 trial
Active Trials
NCT06025396Completed30Est. Jan 2024
NCT06648668Completed18Est. May 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
Soterix Medicaltranscranial direct current stimulator
Tempero BioTMP-301
Tempero BioCohort 1 - TMP-301
Soterix MedicalTranscranial Direct Current Stimulator
Soterix MedicalSoterix Medical mini-CT tDCS stimulator

Clinical Trials (5)

Total enrollment: 48 patients across 5 trials

NCT04994821Soterix Medicaltranscranial direct current stimulator

TDCS to Reduce Craving in Cocaine Addiction- Phase 2 Study

Start: Sep 2020Est. completion: Sep 2022
Phase 2Completed

A Study to Investigate the Interaction Between TMP-301 and Cocaine.

Start: Jan 2025Est. completion: May 202518 patients
Phase 1Completed
NCT06025396Tempero BioCohort 1 - TMP-301

Multiple Ascending Dose Study of TMP-301 in Healthy Subjects

Start: Jan 2023Est. completion: Jan 202430 patients
Phase 1Completed
NCT07318480Soterix MedicalTranscranial Direct Current Stimulator

Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder

Start: Feb 2026Est. completion: Feb 2030
N/ARecruiting
NCT03833583Soterix MedicalSoterix Medical mini-CT tDCS stimulator

TDCS for Cocaine Addiction Craving

Start: Feb 2019Est. completion: Sep 2019
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 48 patients
2 companies competing in this space