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Clostridium Infections

1
Pipeline Programs
3
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
1100%
+ 1 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

ViiV Healthcare
ViiV HealthcareNC - Durham
1 program
1
C. difficile investigational vaccine based on the F2 antigenPhase 1Vaccine1 trial
Active Trials
NCT04026009Completed140Est. May 2022
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
PAR-101/OPT-80PHASE_31 trial
Active Trials
NCT00468728Completed535Est. Dec 2009

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Merck & Co.PAR-101/OPT-80
ViiV HealthcareC. difficile investigational vaccine based on the F2 antigen

Clinical Trials (2)

Total enrollment: 675 patients across 2 trials

PAR-101/OPT-80 Versus Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD)

Start: Oct 2006Est. completion: Dec 2009535 patients
Phase 3Completed
NCT04026009ViiV HealthcareC. difficile investigational vaccine based on the F2 antigen

Safety and Immunogenicity Study of GSK's Clostridium Difficile Vaccine 2904545A When Administered in Healthy Adults Aged 18-45 Years and 50-70 Years

Start: Aug 2019Est. completion: May 2022140 patients
Phase 1Completed

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.