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Clonal Cytopenia of Undetermined Significance

3
Pipeline Programs
3
Companies
3
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
2100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Servier
ServierFrance - Suresnes
1 program
1
IvosidenibPhase 2Small Molecule1 trial
Active Trials
NCT05030441Active Not Recruiting20Est. Jan 2030
Astex Pharmaceuticals
Astex PharmaceuticalsUK - Cambridge
2 programs
2
InqoviPhase 11 trial
cedazuridinePhase 1
Active Trials
NCT06802146Recruiting108Est. Dec 2028
Bristol Myers Squibb
1 program
EnasidenibPHASE_2Small Molecule1 trial
Active Trials
NCT06240754Recruiting15Est. Feb 2029

Trial Timeline

Clinical trial activity over time

2022
2023
2024
2025
2026
2027
2028
2029
2030
Bristol Myers SquibbEnasidenib
ServierIvosidenib
Astex PharmaceuticalsInqovi

Clinical Trials (3)

Total enrollment: 143 patients across 3 trials

Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial

Start: Oct 2024Est. completion: Feb 202915 patients
Phase 2Recruiting

Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

Start: Apr 2022Est. completion: Jan 203020 patients
Phase 2Active Not Recruiting

Early Intervention in High Risk CCUS

Start: Feb 2025Est. completion: Dec 2028108 patients
Phase 1Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 143 patients
Small Molecule is the dominant modality (100% of programs)
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.