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Chronic Rhinosinusitis Without Nasal Polyps

0
Pipeline Programs
4
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 4 programs with unclassified modality

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Regeneron
RegeneronTARRYTOWN, NY
2 programs
ItepekimabPHASE_2Monoclonal Antibody
Dupilumab SAR231893PHASE_3
SynDermix
SynDermixSwitzerland - Hunenberg
1 program
Vibration TherapyN/A1 trial
Active Trials
NCT04158596Withdrawn0Est. Oct 2021
Insmed
InsmedBRIDGEWATER, NJ
1 program
BrensocatibPHASE_21 trial
Active Trials
NCT06013241Completed288Est. Oct 2025
Sanofi
SanofiPARIS, France
1 program
Dupilumab SAR231893PHASE_31 trial
Active Trials
NCT04678856Completed71Est. Jan 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
SanofiDupilumab SAR231893
InsmedBrensocatib
SynDermixVibration Therapy

Clinical Trials (3)

Total enrollment: 359 patients across 3 trials

NCT04678856SanofiDupilumab SAR231893

Dupilumab in CRSsNP

Start: Dec 2020Est. completion: Jan 202471 patients
Phase 3Completed

A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

Start: Oct 2023Est. completion: Oct 2025288 patients
Phase 2Completed
NCT04158596SynDermixVibration Therapy

Safety and Efficacy of SDX-3101 for the Treatment of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

Start: Jun 2020Est. completion: Oct 20210
N/AWithdrawn

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.