Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)

3
Pipeline Programs
2
Companies
2
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
3
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Sanofi
SanofiPARIS, France
2 programs
1
Dupilumab SAR231893Phase 31 trial
Dupilumab - Standard DoseN/A1 trial
Active Trials
NCT06892704Recruiting30Est. Dec 2027
NCT02898454Completed448Est. Nov 2018
Regeneron
RegeneronTARRYTOWN, NY
2 programs
2
Dupilumab SAR231893Phase 3
Dupilumab SAR231893Phase 3

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
SanofiDupilumab SAR231893
SanofiDupilumab - Standard Dose

Clinical Trials (2)

Total enrollment: 478 patients across 2 trials

NCT02898454SanofiDupilumab SAR231893

Controlled Clinical Study of Dupilumab in Patients With Nasal Polyps

Start: Nov 2016Est. completion: Nov 2018448 patients
Phase 3Completed
NCT06892704SanofiDupilumab - Standard Dose

Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients.

Start: May 2025Est. completion: Dec 202730 patients
N/ARecruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 478 patients
2 companies competing in this space