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Chronic Periodontitis

2
Pipeline Programs
5
Companies
5
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 4 programs with unclassified modality

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Himalaya Therapeutics
Himalaya TherapeuticsChina - Hong Kong
1 program
1
Scaling and root planing, and Septilin for 7 daysPhase 21 trial
Active Trials
NCT02013323Completed60Est. Aug 2013
Innovation Pharmaceuticals
1 program
1
Tetracycline-MetronidazolePhase 2Small Molecule1 trial
Active Trials
NCT03656484Completed50Est. Dec 2019
Bayer
BayerLEVERKUSEN, Germany
1 program
Dental examination and a point of care P. gingivalis testN/A1 trial
Active Trials
NCT02672384Completed100Est. Oct 2018
Biolase
BiolaseCA - Foothill Ranch
1 program
Epic DiodePHASE_11 trial
Active Trials
NCT05276817Completed14Est. Dec 2022
Johnson & Johnson
Johnson & JohnsonNEW BRUNSWICK, NJ
1 program
Essential Oils solutionPHASE_41 trial
Active Trials
NCT01195493Completed50Est. Jul 2015

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Johnson & JohnsonEssential Oils solution
Innovation PharmaceuticalsTetracycline-Metronidazole
Himalaya TherapeuticsScaling and root planing, and Septilin for 7 days
BiolaseEpic Diode
BayerDental examination and a point of care P. gingivalis test

Clinical Trials (5)

Total enrollment: 274 patients across 5 trials

NCT01195493Johnson & JohnsonEssential Oils solution

Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care

Start: Mar 2010Est. completion: Jul 201550 patients
Phase 4Completed
NCT03656484Innovation PharmaceuticalsTetracycline-Metronidazole

New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin

Start: Jan 2019Est. completion: Dec 201950 patients
Phase 2Completed
NCT02013323Himalaya TherapeuticsScaling and root planing, and Septilin for 7 days

Clinical and Microbiological Efficacy of Systemic Ayurvedic Immunomodulator Septilin in the Treatment of Chronic Periodontitis

Start: Mar 2013Est. completion: Aug 201360 patients
Phase 2Completed

Perio. Maint. With Diode LBR

Start: Apr 2022Est. completion: Dec 202214 patients
Phase 1Completed
NCT02672384BayerDental examination and a point of care P. gingivalis test

Chronic Periodontitis in Critically Ill Patients: Diagnosis and Epidemiology

Start: Jan 2017Est. completion: Oct 2018100 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.