Chronic Pain
Pipeline by Development Stage
Drug Modality Breakdown
On Market (1)
Approved therapies currently available
Competitive Landscape
48 companies ranked by most advanced pipeline stage
+18 more companies
Trial Timeline
Clinical trial activity over time
Showing 15 of 50 trials with date data
Clinical Trials (50)
Total enrollment: 13,356 patients across 50 trials
Transitioning to a Valve -Gated Intrathecal Drug Delivery System (IDDS)
Targin® for Chronic Pain Management in Patients With Spinal Cord Injury
Pharmacokinetic Study of Hydrocodone/APAP in Chronic Pain Patients
Safety Study to Assess Opiate Withdrawal Signs and Symptoms in Opioid Dependent Patients
Study of Breakthrough Cancer Pain: Assessment of Fentanyl Buccal Tablets Titration and Treatment in Opioid-Tolerant Patients
Spinal Cord Stimulation for Low Back Pain
Tele-Collaborative Outreach to Rural Patients With Chronic Pain
Subdissociative Dose Ketamine for Treatment of Acute Pain in Subjects With Chronic Pain
Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee
Single-arm Study to Assess the Safety of Hydromorphone Hydrochloride by Intrathecal Administration
A Research Study of an Investigational Drug ALO-02 (Oxycodone Hydrochloride and Naltrexone Hydrochloride) in Patients With Moderate to Severe Chronic Low Back Pain
Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time
Long-Term Study of Hydrocodone Bitartrate Controlled-release Capsules in Subjects With Chronic Pain
Cognitive Function and Addiction Under Opioid Tapering
Fentanyl Buccal Tablets Versus Immediate Release Oxycodone for Breakthrough Pain in Patients With Chronic Pain
Buprenorphine Transdermal System (BTDS) in Subjects w/Mod-sev Osteoarthritis (OA) Chronic Pain of Knee
Efficacy and Safety of Fentanyl Buccal Tablets Compared With Oxycodone for the Management of Break Through Pain
An Implantable Spinal Cord Stimulation Pain Management System
A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)
A Study Comparing the Effectiveness and Safety of Varying Dose Strengths (100, 200, 300 and 400 mg) of Extended-release Tramadol HCl With Placebo for the Treatment of Osteoarthritis(OA) of the Knee and/or Hip
Safety and Effectiveness of Buprenorphine Transdermal System in Elderly Subjects With Chronic Pain: Pilot Study.
A Study Comparing the Effectiveness and Safety of Extended Release Tramadol Versus Placebo for the Treatment of Osteoarthritis (OA) of the Knee
A Study Comparing the Effectiveness and Safety of Extended-release Tramadol Versus Placebo in the Treatment of Chronic Low Back Pain
A One-year, Open-label Study to Assess the Safety and Effectiveness of Extended Release Tramadol HCl in the Treatment of Chronic, Non-malignant Pain.
Cannabis Oil for Pain Effectiveness
Safety and Efficacy of Medical Cannabis Oil in the Treatment of Patients with Chronic Pain
Fentanyl Buccal Tablet for the Relief of Episodic Breathlessness in Cancer Patients
Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD
A Study to Test the Effects of Kindolor at Different Doses in Healthy Adults
Lumbar Injectrode Feasibility Evaluation
Multiple Dose Study of Safety and Pharmacokinetics of MEDI0618 in Healthy Volunteers
PET/MRI in the Diagnosis of Pediatric Chronic Pain
A Study of the Safety, Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers
A Study to Evaluate the Safety and Pharmacokinetics of CNTX-6016 in Healthy Subjects
A Placebo-Controlled, Two-Part Study, Oral Dose to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of CNTX-6970 in Healthy Subjects
A Study of MEDI7352 in Painful Osteoarthritis of the Knee
Use of PET/MR Imaging in Chronic Pain
A Study To Observe The Performance Of A Tablet Form Of PF-04531083 As Evidenced By The Concentration Of PF-04531083 In The Blood With Time Following Oral Administration To Healthy Volunteers.
AZD2066 Cocktail Study
AZD1386 Japanese Multiple Ascending Dosing Study
Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1386
Immunologic Response to Negative Cognition in Persons With Chronic Pain
Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain
EVA: Evaluation of EVOKE Therapy Metrics Generated Using the Evoke System With EVA
Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control
Effectiveness of a Digital Treatment for Adolescents with Chronic Pain
Empowered Relief: A One-Time Session to Help Postpartum Women Manage Ongoing Pain After Cesarean Delivery
The PROmoting Pain Self-Management (PROs) Trial: Holistic Pain Care in the Military Health System
Virtual Reality Treatment for Adults With Chronic Back Pain (VRNT)
Comparison of the Efficacy of an Empowered Relief Single-Session Versus Standard Care for Reducing Postoperative Pain Following Elective Orthopedic Surgery: A Randomized Controlled Trial
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