Chronic Low-Back Pain

0
Pipeline Programs
5
Companies
14
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

AM-Pharma
AM-PharmaNetherlands - Utrecht
1 program
AuriMod CT01_AN/A1 trial
Active Trials
NCT04753528CompletedEst. Oct 2022
Tabuk Pharmaceuticals
Tabuk PharmaceuticalsSaudi Arabia - Riyadh
1 program
Kinesio tapingN/A1 trial
Active Trials
NCT05173948CompletedEst. Aug 2020
Biotronik
BiotronikGermany - Berlin
1 program
Permanent implant of a BIOTRONIK Prospera SCSN/A1 trial
Active Trials
NCT04683718Active Not Recruiting60Est. Jan 2027
Mainstay Medical
Mainstay MedicalIreland - Dublin
1 program
ReActiv8N/A1 trial
Active Trials
NCT04803214Completed203Est. Jan 2026
Abbott
AbbottABBOTT PARK, IL
1 program
Spinal Cord StimulationN/A5 trials
Active Trials
NCT07250828Enrolling By Invitation20Est. May 2027
NCT05877612Unknown30Est. Sep 2025
NCT06030284Withdrawn0Est. Jun 2023
+2 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
AbbottSpinal Cord Stimulation
AbbottSpinal Cord Stimulation
AbbottSpinal Cord Stimulation
AbbottSpinal Cord Stimulation
AbbottSpinal Cord Stimulation
BiotronikPermanent implant of a BIOTRONIK Prospera SCS
Mainstay MedicalReActiv8
AbbottSpinal Cord Stimulation
AM-PharmaAuriMod CT01_A
AbbottSpinal Cord Stimulation
Tabuk PharmaceuticalsKinesio taping
AbbottSpinal Cord Stimulation
AbbottSpinal Cord Stimulation
AbbottSpinal Cord Stimulation

Clinical Trials (14)

Total enrollment: 1,292 patients across 14 trials

NCT01362725AbbottSpinal Cord Stimulation

Spinal Cord Stimulation For Heart Failure

Start: Apr 2011Est. completion: Jan 201620 patients
Phase 2/3Completed
NCT07250828AbbottSpinal Cord Stimulation

Efficacy and Feasibility of BurstDR SCS in Painful Diabetic Neuropathy

Start: Dec 2025Est. completion: May 202720 patients
N/AEnrolling By Invitation
NCT05877612AbbottSpinal Cord Stimulation

Efficacy of Spinal Cord Stimulation in Burst Mode in the Treatment of Complex Regional Pain Syndromes Type 1 of the Upper Limbs

Start: Sep 2023Est. completion: Sep 202530 patients
N/AUnknown
NCT06030284AbbottSpinal Cord Stimulation

The True Efficacy of Burst Spinal Cord Stimulation in the Management of Intractable Low Back Pain (TRU-BURST)

Start: Apr 2023Est. completion: Jun 20230
N/AWithdrawn
NCT05590000AbbottSpinal Cord Stimulation

Study of Gemini Rechargeable Spinal Cord Stimulation (SCS) System

Start: Sep 2022Est. completion: Feb 202325 patients
N/ACompleted
NCT04683718BiotronikPermanent implant of a BIOTRONIK Prospera SCS

A First in Human Feasibility Study to Evaluate the Safety and Effectiveness of the BIOTRONIK Prospera SCS System with HomeStream Remote Management

Start: Sep 2021Est. completion: Jan 202760 patients
N/AActive Not Recruiting

ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation

Start: Jul 2021Est. completion: Jan 2026203 patients
N/ACompleted
NCT05659836AbbottSpinal Cord Stimulation

Spinal Cord Stimulation Trial to Permanent Prediction

Start: May 2021Est. completion: Jun 202328 patients
N/ACompleted
NCT04753528AM-PharmaAuriMod CT01_A

Personalized Auricular Vagus Nerve Stimulation in Intractable Chronic Low Back Pain

Start: Apr 2021Est. completion: Oct 2022
N/ACompleted
NCT04479787AbbottSpinal Cord Stimulation

Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)

Start: Jul 2020Est. completion: Feb 2024270 patients
N/ACompleted

The Effectiveness of Kinesio Taping in Patients With Chronic Low Back Pain

Start: Jun 2019Est. completion: Aug 2020
N/ACompleted
NCT03159169AbbottSpinal Cord Stimulation

Treatment of Neck and Upper Limb Pain Using BurstDR (De Ridder) Stimulation

Start: May 2018Est. completion: Aug 202217 patients
N/ATerminated
NCT02250469AbbottSpinal Cord Stimulation

A Randomised Pilot Study to Assess Differences in Stimulation Induced Paresthesia Between 2 Spinal Cord Stimulation Systems

Start: Sep 2014Est. completion: Dec 20165 patients
N/ATerminated
NCT01305525AbbottSpinal Cord Stimulation

A Prospective Clinical Outcomes Registry

Start: Jun 2009Est. completion: Apr 2014614 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

5 companies competing in this space