Chikungunya Virus

5
Pipeline Programs
2
Companies
5
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
3
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
1100%
+ 4 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Bavarian Nordic
Bavarian NordicDenmark - Kvistgard
4 programs
1
3
CHIKV VLP vaccinePhase 3Vaccine1 trial
CHIKV VLP/adjuvantPhase 31 trial
CHIKV VLP/adjuvantPhase 31 trial
CHIKV VLP, adjuvantedPhase 21 trial
Active Trials
NCT05065983Completed25Est. May 2022
NCT07003984Recruiting720Est. Dec 2028
NCT05072080Completed3,258Est. Apr 2023
+1 more trials
Moderna
ModernaCAMBRIDGE, MA
1 program
1
VAL-181388Phase 11 trial
Active Trials
NCT03325075Completed60Est. Mar 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Bavarian NordicCHIKV VLP vaccine
Bavarian NordicCHIKV VLP/adjuvant
Bavarian NordicCHIKV VLP/adjuvant
Bavarian NordicCHIKV VLP, adjuvanted
ModernaVAL-181388

Clinical Trials (5)

Total enrollment: 4,476 patients across 5 trials

A Safety and Immunogenicity Study of CHIKV VLP Vaccine in Children.

Start: Jun 2025Est. completion: Dec 2028720 patients
Phase 3Recruiting
NCT05349617Bavarian NordicCHIKV VLP/adjuvant

Safety and Immunogenicity of CHIKV VLP Vaccine PXVX0317 in Adults ≥65 Years

Start: May 2022Est. completion: Aug 2023413 patients
Phase 3Completed
NCT05072080Bavarian NordicCHIKV VLP/adjuvant

A Phase 3 Trial of the VLP-Based Chikungunya Vaccine PXVX0317 (CHIKV VLP Vaccine)

Start: Sep 2021Est. completion: Apr 20233,258 patients
Phase 3Completed
NCT05065983Bavarian NordicCHIKV VLP, adjuvanted

A Study to Assess the Safety and Immunogenicity of PXVX0317 Chikungunya Virus Virus-Like Particle Vaccine

Start: Oct 2021Est. completion: May 202225 patients
Phase 2Completed

Safety, Tolerability, and Immunogenicity of VAL-181388 in Healthy Participants

Start: Jul 2017Est. completion: Mar 201960 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 4,476 patients
2 companies competing in this space