Cervical Dystonia

12
Pipeline Programs
4
Companies
13
Clinical Trials
1 recruiting
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
3
0
6
3
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

Ipsen
DYSPORTApproved
botulinum toxin type a
Ipsen
Acetylcholine Release Inhibitor [EPC]injection2009

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Ipsen
IpsenChina - Tianjin
10 programs
1
6
1
Dysport®Phase 41 trial
Botulinum toxin type APhase 31 trial
Botulinum toxin type APhase 31 trial
Botulinum toxin type APhase 31 trial
Botulinum toxin type APhase 31 trial
+5 more programs
Active Trials
NCT01753349Completed1,050Est. Sep 2017
NCT01314365Completed350Est. Mar 2014
NCT06937931Recruiting132Est. Nov 2027
+7 more trials
US WorldMeds
US WorldMedsKY - Louisville
1 program
1
Botulinum Toxin Type BPhase 41 trial
Active Trials
NCT00702754CompletedEst. Sep 2008
E
EisaiChina - Liaoning
1 program
1
BOTULINUM TOXIN TYPE BPhase 21 trial
Active Trials
NCT00165776Completed133Est. Nov 2006
Motric Bio
Motric BioCA - Oakland
1 program
1
MTR-601Phase 21 trial
Active Trials
NCT06830642SuspendedEst. Aug 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
IpsenDysport®
US WorldMedsBotulinum Toxin Type B
IpsenBotulinum toxin type A
IpsenBotulinum toxin type A
IpsenBotulinum toxin type A
IpsenBotulinum toxin type A
IpsenBotulinum toxin type A
IpsenBotulinum toxin type A
IpsenIPN10200
Motric BioMTR-601
EisaiBOTULINUM TOXIN TYPE B
IpsenBotulinum toxin type A
IpsenDYSPORT™ Clinical & Health Economics Outcomes Registry in Cervical Dystonia

Clinical Trials (13)

Total enrollment: 3,136 patients across 13 trials

NCT00950664IpsenDysport®

A Study to Compare Dysport® and Botox® in the Treatment of Cervical Dystonia

Start: Aug 2009Est. completion: Jul 2011103 patients
Phase 4Completed
NCT00702754US WorldMedsBotulinum Toxin Type B

An Open Label Safety and Immunogenicity Study of MYOBLOC (Neurobloc; Botulinum Toxin Type B) Injectable Solution in Patients With Cervical Dystonia

Start: Jun 2001Est. completion: Sep 2008
Phase 4Completed
NCT01753336IpsenBotulinum toxin type A

Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia

Start: Mar 2013Est. completion: Oct 2015112 patients
Phase 3Completed
NCT01753310IpsenBotulinum toxin type A

Efficacy and Safety of DYSPORT® Using 2mL Dilution in Adults With Cervical Dystonia.

Start: Jan 2013Est. completion: Jan 2015134 patients
Phase 3Completed
NCT01261611IpsenBotulinum toxin type A

Study Comparing Short Term Efficacy of Dysport and Dysport NG to Placebo, and to Assess Efficacy and Safety of Dysport NG of Subjects With Cervical Dystonia

Start: Apr 2011Est. completion: Jun 2013382 patients
Phase 3Completed
NCT00288509IpsenBotulinum toxin type A

Open-label Extension Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia

Start: Feb 2006Est. completion: Jan 2008108 patients
Phase 3Completed
NCT00257660IpsenBotulinum toxin type A

Randomized, Placebo-Controlled Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia

Start: Oct 2005Est. completion: Sep 2006116 patients
Phase 3Completed
NCT00447772IpsenBotulinum toxin type A

Study to Assess the Efficacy and Safety of Dysport® in Cervical Dystonia

Start: Oct 2004Est. completion: Apr 2008516 patients
Phase 3Completed
NCT06937931IpsenIPN10200

A Study of IPN10200 for the Treatment of Cervical Dystonia in Adults

Start: Jun 2025Est. completion: Nov 2027132 patients
Phase 2Recruiting
NCT06830642Motric BioMTR-601

Study of the Oral Treatment MTR-601 in Cervical Dystonia

Start: Feb 2025Est. completion: Aug 2026
Phase 2Suspended
NCT00165776EisaiBOTULINUM TOXIN TYPE B

Randomized, Double-Blind, Placebo-Controlled, Parallel, Group Dose-Response, Study of E2014 in Patients WIth Spasmodic Torticollis

Start: Jun 2004Est. completion: Nov 2006133 patients
Phase 2Completed
NCT01753349IpsenBotulinum toxin type A

Phase IV-Cervical Dystonia-INTEREST IN CD2

Start: Dec 2012Est. completion: Sep 20171,050 patients
N/ACompleted
NCT01314365IpsenDYSPORT™ Clinical & Health Economics Outcomes Registry in Cervical Dystonia

DYSPORT™ Clinical & Health Economics Outcomes Registry in Cervical Dystonia

Start: Apr 2011Est. completion: Mar 2014350 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

6 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 3,136 patients
4 companies competing in this space