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Cervical Disc Disease

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Pipeline Programs
4
Companies
6
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

NuVasive
NuVasiveCA - San Diego
3 programs
CerPass® Total Disc ReplacementN/A
NuVasive Simplify Cervical Artificial DiscN/A
NuVasive Simplify Cervical Artificial DiscN/A
Globus Medical
Globus MedicalAUDUBON, PA
3 programs
CerPass® Total Disc ReplacementN/A1 trial
NuVasive Simplify Cervical Artificial DiscN/A1 trial
NuVasive Simplify Cervical Artificial DiscN/A1 trial
Active Trials
NCT01433367Terminated2Est. Dec 2013
NCT05691231Enrolling By Invitation158Est. May 2029
NCT05258435Active Not Recruiting131Est. Apr 2028
Spineart
SpineartSwitzerland - Plan-Les-Ouates
2 programs
BAGUERA®C Cervical Disc ProsthesisN/A1 trial
BAGUERA®C Cervical Disc ProsthesisN/A1 trial
Active Trials
NCT04520776Unknown284Est. Feb 2026
NCT04564885Active Not Recruiting300Est. Apr 2030
Spine BioPharma
Spine BioPharmaNY - New York
1 program
Mobi-CN/A1 trial
Active Trials
NCT03077516Completed216Est. Oct 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
Globus MedicalNuVasive Simplify Cervical Artificial Disc
Globus MedicalNuVasive Simplify Cervical Artificial Disc
SpineartBAGUERA®C Cervical Disc Prosthesis
SpineartBAGUERA®C Cervical Disc Prosthesis
Spine BioPharmaMobi-C
Globus MedicalCerPass® Total Disc Replacement

Clinical Trials (6)

Total enrollment: 1,091 patients across 6 trials

NCT05691231Globus MedicalNuVasive Simplify Cervical Artificial Disc

Long-Term Assessment of the Safety and Performance of the NuVasive Simplify Disc at Two Levels

Start: Jan 2023Est. completion: May 2029158 patients
N/AEnrolling By Invitation
NCT05258435Globus MedicalNuVasive Simplify Cervical Artificial Disc

Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc

Start: Feb 2022Est. completion: Apr 2028131 patients
N/AActive Not Recruiting
NCT04520776SpineartBAGUERA®C Cervical Disc Prosthesis

A Clinical Trial Comparing the BAGUERA C to the Marketed Mobi-C® for the Treatment of Single Level Cervical Disc Disease

Start: Mar 2021Est. completion: Feb 2026284 patients
N/AUnknown
NCT04564885SpineartBAGUERA®C Cervical Disc Prosthesis

A Clinical Trial Comparing the BAGUERA C to the Marketed Mobi-C® for the Treatment of Cervical Disc Disease at 2 Contiguous Levels

Start: Mar 2021Est. completion: Apr 2030300 patients
N/AActive Not Recruiting

Post-Market, Long-Term Follow Up of Mobi-C® Cervical Disc for One and Two Level Treatment of Cervical Disc Disease

Start: Nov 2016Est. completion: Oct 2019216 patients
N/ACompleted
NCT01433367Globus MedicalCerPass® Total Disc Replacement

A Clinical Trial Evaluating a Total Disc Replacement in Patients With Cervical Disc Disease

Start: May 2010Est. completion: Dec 20132 patients
N/ATerminated

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.