Cerebrospinal Fluid Leak
2
Pipeline Programs
4
Companies
3
Clinical Trials
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
3 companies ranked by most advanced pipeline stage
Baxter InternationalDEERFIELD, IL
2 programs1
FS VH S/D 500 s-aprPhase 3
FS VH S/D 500 s-aprPHASE_31 trial
Active Trials
UNION therapeuticsDenmark - Hellerup
1 program1
Absorbable Medical AdhesivePhase 31 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
UNION therapeuticsAbsorbable Medical Adhesive
Baxter InternationalFS VH S/D 500 s-apr
Integra LifeSciencesSuturable DuraGen™
Clinical Trials (3)
Total enrollment: 462 patients across 3 trials
A Trial of Absorbable Medical Adhesive for Prevention of CSF Leak
Start: Nov 2017Est. completion: Sep 2021132 patients
Phase 3Completed
Efficacy and Safety of FS VH S/D 500 S-apr (Tisseel) as an Adjunct to Sutured Dural Repair in Cranial Surgery
Start: Oct 2016Est. completion: Aug 2018224 patients
Phase 3Completed
Suturable DuraGen™ PMCF Study
Start: Apr 2021Est. completion: Jul 2024106 patients
N/ACompleted
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
2 late-stage (Phase 3) programs, potential near-term approvals
4 companies competing in this space
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.