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Cerebral Cavernous Malformation

1
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 1 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

ETS
ETSMO - Rolla
1 program
1
PropranololPhase 2Small Molecule1 trial
Active Trials
NCT03589014Completed71Est. Dec 2021
Recursion Pharmaceuticals
Recursion PharmaceuticalsSALT LAKE CITY, UT
1 program
REC-994PHASE_21 trial
Active Trials
NCT05085561Completed62Est. Jun 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Recursion PharmaceuticalsREC-994
ETSPropranolol

Clinical Trials (2)

Total enrollment: 133 patients across 2 trials

The Symptomatic Cerebral Cavernous Malformation Trial of REC-994

Start: Mar 2022Est. completion: Jun 202562 patients
Phase 2Completed
NCT03589014ETSPropranolol

Treat_CCM: Propranolol in Familial Cerebral Cavernous Malformation

Start: Apr 2018Est. completion: Dec 202171 patients
Phase 2Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.