Skip to main content

Cartilage Injury

1
Pipeline Programs
5
Companies
5
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

TBF Genie Tissulaire
TBF Genie TissulaireFrance - Mions
1 program
1
OD-PHOENIXPhase 1/21 trial
Active Trials
NCT02430558Terminated10Est. Jun 2021
BioPoly
BioPolyIN - Fort Wayne
1 program
BioPoly RS Partial Resurfacing Knee ImplantN/A1 trial
Active Trials
NCT01473199Completed38Est. Dec 2021
Hyalex Orthopaedics
Hyalex OrthopaedicsMA - Lexington
1 program
SurgicalN/A1 trial
Active Trials
NCT06344481Recruiting15Est. Sep 2026
MEDIPOST
MEDIPOSTKorea - Gyeonggi
1 program
CartistemPHASE_31 trial
Active Trials
NCT01041001Completed104Est. Jan 2011
Geistlich Pharma
Geistlich PharmaSwitzerland - Root
1 program
MicrofracturePHASE_31 trial
Active Trials
NCT02993510Completed67Est. Jul 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
MEDIPOSTCartistem
Geistlich PharmaMicrofracture
TBF Genie TissulaireOD-PHOENIX
Hyalex OrthopaedicsSurgical
BioPolyBioPoly RS Partial Resurfacing Knee Implant

Clinical Trials (5)

Total enrollment: 234 patients across 5 trials

NCT01041001MEDIPOSTCartistem

Study to Compare Efficacy and Safety of Cartistem and Microfracture in Patients With Knee Articular Cartilage Injury

Start: Feb 2009Est. completion: Jan 2011104 patients
Phase 3Completed
NCT02993510Geistlich PharmaMicrofracture

A Randomized Controlled Trial Comparing Chondro-Gide® to Microfracture Alone for Treatment of Knee Cartilage Defects.

Start: Dec 2003Est. completion: Jul 201667 patients
Phase 3Completed
NCT02430558TBF Genie TissulaireOD-PHOENIX

Second Line Treatment of Knee Osteochondral Lesion With Treated Osteochondral Graft

Start: Apr 2016Est. completion: Jun 202110 patients
Phase 1/2Terminated
NCT06344481Hyalex OrthopaedicsSurgical

The Hyalex First-in-Human Study

Start: Mar 2024Est. completion: Sep 202615 patients
N/ARecruiting
NCT01473199BioPolyBioPoly RS Partial Resurfacing Knee Implant

BioPoly RS Knee Registry Study for Cartilage Defect Replacement

Start: Nov 2011Est. completion: Dec 202138 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 234 patients
5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.