Skip to main content

Cardiac Surgical Procedures

3
Pipeline Programs
8
Companies
8
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

8 companies ranked by most advanced pipeline stage

UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
1
Prothrombin Complex Concentrate, HumanPhase 41 trial
Active Trials
NCT04244981Recruiting820Est. Oct 2025
CSL Seqirus
CSL SeqirusUK - Maidenhead
1 program
1
Fibrinogen concentratePhase 2
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
1
DexmedetominePhase 11 trial
Active Trials
NCT00459082Completed36Est. Nov 2006
Medtronic
MedtronicNJ - Phillipsburg
2 programs
Lead Extract StudyN/A1 trial
Veriset Hemostatic PatchN/A1 trial
Active Trials
NCT01169441Completed100Est. May 2010
NCT01639833Completed90Est. Dec 2013
XVIVO
XVIVOSweden - Mölndal
1 program
Colloid priming solution for ECC circuitN/A1 trial
Active Trials
NCT04293744Terminated100Est. Oct 2023
Zimmer Biomet
Zimmer BiometFL - Jacksonville
1 program
SternaLock BluN/A1 trial
Active Trials
NCT03709693Terminated156Est. May 2020
CSL Behring
CSL BehringIL - Bradley
1 program
Fibrinogen concentratePHASE_21 trial
Active Trials
NCT01187225Completed63Est. Nov 2011
Novo Nordisk
Novo NordiskBAGSVAERD DENMARK, Denmark
1 program
Insulin infusion with a goalPHASE_31 trial
Active Trials
NCT00282698Completed400Est. May 2005

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
UNION therapeuticsProthrombin Complex Concentrate, Human
Novo NordiskInsulin infusion with a goal
CSL BehringFibrinogen concentrate
Human BioSciencesDexmedetomine
XVIVOColloid priming solution for ECC circuit
Zimmer BiometSternaLock Blu
MedtronicVeriset Hemostatic Patch
MedtronicLead Extract Study

Clinical Trials (8)

Total enrollment: 1,765 patients across 8 trials

NCT04244981UNION therapeuticsProthrombin Complex Concentrate, Human

Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery

Start: Oct 2023Est. completion: Oct 2025820 patients
Phase 4Recruiting
NCT00282698Novo NordiskInsulin infusion with a goal

Outcomes With Tight Control of Hyperglycemia in Cardiac Surgery Patients

Start: Jul 2004Est. completion: May 2005400 patients
Phase 3Completed
NCT01187225CSL BehringFibrinogen concentrate

Fibrinogen Concentrate In Children After Cardiac Surgery

Start: Aug 2010Est. completion: Nov 201163 patients
Phase 2Completed
NCT00459082Human BioSciencesDexmedetomine

A Pharmacokinetic Study of Dexmedetomine in Infants

Start: May 2004Est. completion: Nov 200636 patients
Phase 1Completed
NCT04293744XVIVOColloid priming solution for ECC circuit

Acute Kidney Injury After Cardiac Surgery

Start: Sep 2020Est. completion: Oct 2023100 patients
N/ATerminated
NCT03709693Zimmer BiometSternaLock Blu

Clinical Outcomes in Patients Treated With SternaLock Blu

Start: May 2019Est. completion: May 2020156 patients
N/ATerminated
NCT01639833MedtronicVeriset Hemostatic Patch

A Premarket, Prospective, Randomized, Single-Blind Study to Compare the Veriset™ Hemostatic Patch to TachoSil® as an Adjunct to Hemostasis in Subjects Undergoing Cardiovascular Surgery

Start: Aug 2012Est. completion: Dec 201390 patients
N/ACompleted
NCT01169441MedtronicLead Extract Study

Lead Extract Study

Start: Nov 2006Est. completion: May 2010100 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 1,765 patients
8 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.