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Cardiac Resynchronization Therapy

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Pipeline Programs
6
Companies
7
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Abbott
AbbottABBOTT PARK, IL
2 programs
Cardiac resynchronization therapy by CRT-P or CRT-D implantationN/A1 trial
MPP + SyncAVN/A1 trial
Active Trials
NCT04595305Completed3Est. Aug 2022
NCT06444386Completed30Est. Apr 2024
Boston Scientific
Boston ScientificCA - Valencia
1 program
ACUITY X4 quadripolar coronary venous lead and RELIANCE 4-FRONT defibrillation leadN/A1 trial
Active Trials
NCT02071173Completed2,244Est. Oct 2020
Medtronic
MedtronicNJ - Phillipsburg
1 program
Postero-lateralN/A1 trial
Active Trials
NCT01515761Unknown60
Rhine Pharma
Rhine PharmaGermany - Heidelberg
1 program
Vector optimisationN/A1 trial
Active Trials
NCT03092349Terminated10Est. Dec 2018
EBR Systems
EBR SystemsSUNNYVALE, CA
1 program
WiCS-LV SystemN/A1 trial
Active Trials
NCT02610673Active Not Recruiting100Est. Jun 2027
Stereotaxis
StereotaxisST.LOUIS, MO
1 program
Bi-ventricular lead placementPHASE_41 trial
Active Trials
NCT00370474Terminated27Est. Sep 2006

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
StereotaxisBi-ventricular lead placement
AbbottMPP + SyncAV
AbbottCardiac resynchronization therapy by CRT-P or CRT-D implantation
Rhine PharmaVector optimisation
EBR SystemsWiCS-LV System
Boston ScientificACUITY X4 quadripolar coronary venous lead and RELIANCE 4-FRONT defibrillation lead
MedtronicPostero-lateral

Clinical Trials (7)

Total enrollment: 2,474 patients across 7 trials

NCT00370474StereotaxisBi-ventricular lead placement

MAGNET CRT Feasibility - Efficiency of LV Lead Placement Comparing Conventional vs. Magnetic Guidance

Start: Jun 2006Est. completion: Sep 200627 patients
Phase 4Terminated
NCT06444386AbbottMPP + SyncAV

ECGi of SyncAV With MultiPoint Pacing

Start: Sep 2021Est. completion: Apr 202430 patients
N/ACompleted
NCT04595305AbbottCardiac resynchronization therapy by CRT-P or CRT-D implantation

Septal Mapping And Resynchronisation Therapy- (SMART) Study

Start: Sep 2019Est. completion: Aug 20223 patients
N/ACompleted
NCT03092349Rhine PharmaVector optimisation

SonR Based Stimulation-VECtor OPTimisation in CRT Patients

Start: Jan 2017Est. completion: Dec 201810 patients
N/ATerminated
NCT02610673EBR SystemsWiCS-LV System

WiCS-LV Post Market Surveillance Registry

Start: Feb 2016Est. completion: Jun 2027100 patients
N/AActive Not Recruiting
NCT02071173Boston ScientificACUITY X4 quadripolar coronary venous lead and RELIANCE 4-FRONT defibrillation lead

Evaluation of ACUITY™ X4 Quadripolar Coronary Venous Leads and RELIANCE™ 4-FRONT Defibrillation Leads

Start: Apr 2014Est. completion: Oct 20202,244 patients
N/ACompleted
NCT01515761MedtronicPostero-lateral

POsition of Leads in Advanced heaRt Failure: the POLAR Study

Start: Sep 201060 patients
N/AUnknown

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.