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Cardiac Arrest, Out-Of-Hospital

3
Pipeline Programs
3
Companies
3
Clinical Trials
1 recruiting
2
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
3
Early DiscoveryClinical DevelopmentMarket

On Market (2)

Approved therapies currently available

Pfizer
ADRENALINApproved
epinephrine
Pfizer
alpha-Adrenergic Agonist [EPC]intramuscular, intravenous, subcutaneous2012
51K Part D
Pfizer
PRIMATENE MISTApproved
epinephrine
Pfizer
inhalation1967

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
1 program
1
EpinephrinePhase 41 trial
Active Trials
NCT03826524Recruiting3,790Est. Dec 2028
Zoll
ZollCA - San Jose
1 program
AED 3 with Uni-padzN/A1 trial
Active Trials
NCT05013333Active Not Recruiting38Est. Feb 2029
Stryker
StrykerCA - San Jose
1 program
LUCAS 2 Active Decompression 2N/A1 trial
Active Trials
NCT04891380Completed183Est. Jan 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
PfizerEpinephrine
StrykerLUCAS 2 Active Decompression 2
ZollAED 3 with Uni-padz

Clinical Trials (3)

Total enrollment: 4,011 patients across 3 trials

Epinephrine Dose: Optimal Versus Standard Evaluation Trial

Start: May 2023Est. completion: Dec 20283,790 patients
Phase 4Recruiting
NCT04891380StrykerLUCAS 2 Active Decompression 2

BCG Biosensor and Non- and Invasive Monitoring During Emergency Medicine Cases, a Prospective Feasibility Study

Start: May 2021Est. completion: Jan 2024183 patients
N/ACompleted
NCT05013333ZollAED 3 with Uni-padz

AED 3 Post-Approval Study

Start: Mar 2021Est. completion: Feb 202938 patients
N/AActive Not Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 4,011 patients
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.