Cardiac Arrest

3
Pipeline Programs
4
Companies
9
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
1
0
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

One Biosciences
One BiosciencesFrance - Paris
3 programs
1
1
1
DefibrillationPhase 41 trial
Up to 2 liter infusion of cold 4 degree C normal salinePhase 1/21 trial
nitritePhase 11 trial
Active Trials
NCT01178359CompletedEst. Apr 2016
NCT00329563CompletedEst. Mar 2006
NCT00101881CompletedEst. Jan 2005
Zoll
ZollCA - San Jose
4 programs
AutoPulseN/A1 trial
Quality of Pediatric Resuscitation in a Multicenter CollaborativeN/A1 trial
RapidShockN/A1 trial
ZOLL Intravascular Temperature Management SystemN/A1 trial
Active Trials
NCT00597207CompletedEst. Dec 2013
NCT02708134RecruitingEst. Jan 2030
NCT04014842CompletedEst. Dec 2023
+1 more trials
Getinge
GetingeChina - Suzhou
1 program
Extracorporeal cardiopulmonary resuscitationN/A1 trial
Active Trials
NCT03101787Completed134Est. Feb 2022
CytoSorbents
CytoSorbentsPRINCETON, NJ
1 program
HemoadsorptionN/A1 trial
Active Trials
NCT03632837Unknown40Est. Sep 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
One BiosciencesDefibrillation
One BiosciencesUp to 2 liter infusion of cold 4 degree C normal saline
One Biosciencesnitrite
ZollRapidShock
CytoSorbentsHemoadsorption
GetingeExtracorporeal cardiopulmonary resuscitation
ZollQuality of Pediatric Resuscitation in a Multicenter Collaborative
ZollZOLL Intravascular Temperature Management System
ZollAutoPulse

Clinical Trials (9)

Total enrollment: 174 patients across 9 trials

NCT00101881One BiosciencesDefibrillation

Transthoracic Incremental Monophasic Versus Biphasic by Emergency Responders (TIMBER)

Start: Nov 2002Est. completion: Jan 2005
Phase 4Completed
NCT00329563One BiosciencesUp to 2 liter infusion of cold 4 degree C normal saline

Pilot Community Clinical Study of Hypothermia in Cardiac Arrest

Start: Nov 2004Est. completion: Mar 2006
Phase 1/2Completed
NCT01178359One Biosciencesnitrite

Pilot Study of Sodium Nitrite in Resuscitated Cardiac Arrest Patients

Start: Jan 2010Est. completion: Apr 2016
Phase 1Completed
NCT04014842ZollRapidShock

RapidShock Post-Approval Study

Start: Feb 2019Est. completion: Dec 2023
N/ACompleted
NCT03632837CytoSorbentsHemoadsorption

HaemoAdsorption Nach Reanimation An ECMO

Start: Oct 2018Est. completion: Sep 201940 patients
N/AUnknown
NCT03101787GetingeExtracorporeal cardiopulmonary resuscitation

Early Initiation of Extracorporeal Life Support in Refractory OHCA

Start: May 2017Est. completion: Feb 2022134 patients
N/ACompleted
NCT02708134ZollQuality of Pediatric Resuscitation in a Multicenter Collaborative

Quality of Pediatric Resuscitation in a Multicenter Collaborative

Start: May 2016Est. completion: Jan 2030
N/ARecruiting
NCT01847482ZollZOLL Intravascular Temperature Management System

Therapeutic Hypothermia With IntraVascular Temperature Management (IVTM) in Post-Cardiogenic Cardiac Arrest and Post-Return of Spontaneous Circulation Patients in Japan

Start: Mar 2013Est. completion: Jan 2016
N/ACompleted
NCT00597207ZollAutoPulse

Circulation Improving Resuscitation Care (CIRC)

Start: Jan 2008Est. completion: Dec 2013
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 174 patients
4 companies competing in this space