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Calciphylaxis

3
Pipeline Programs
4
Companies
2
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
1
1
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

Hope Pharmaceuticals
SODIUM THIOSULFATEApproved
sodium thiosulfate
Hope Pharmaceuticals
intravenous2012

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Hope Pharmaceuticals
Hope PharmaceuticalsAZ - Scottsdale
1 program
1
1
Sodium ThiosulfatePhase 31 trial
Active Trials
NCT03150420Terminated29Est. Apr 2020
Inozyme Pharma
Inozyme PharmaMA - Boston
1 program
1
INZ-701Phase 11 trial
Active Trials
NCT06283589Completed11Est. Dec 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Hope PharmaceuticalsSodium Thiosulfate
Inozyme PharmaINZ-701

Clinical Trials (2)

Total enrollment: 40 patients across 2 trials

A Phase 3 Clinical Trial of Intravenous Sodium Thiosulfate in Acute Calciphylaxis Patients

Start: May 2017Est. completion: Apr 202029 patients
Phase 3Terminated

The SEAPORT 1 Study: Evaluation of the Safety and Tolerability of INZ-701 in Adults With End-Stage Kidney Disease Undergoing Hemodialysis

Start: Feb 2024Est. completion: Dec 202411 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.