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Brain Diseases

2
Pipeline Programs
9
Companies
7
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Abbott
AbbottABBOTT PARK, IL
1 program
1
ABT-888Phase 11 trial
Active Trials
NCT00649207Completed80Est. Mar 2013
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
1
ABT-888Phase 1
MicroPort
MicroPortChina - Shanghai
4 programs
BridgeN/A
Intracranial stent for wide-necked aneurysmsN/A
Intracranial stent for wide-necked aneurysmsN/A
TubridgeN/A
Neurotech Pharmaceuticals
4 programs
BridgeN/A1 trial
Intracranial stent for wide-necked aneurysmsN/A1 trial
Intracranial stent for wide-necked aneurysmsN/A1 trial
TubridgeN/A1 trial
Active Trials
NCT06186024Unknown36Est. Jan 2025
NCT05275296Unknown200Est. Dec 2023
NCT06189950Recruiting200Est. Oct 2026
+1 more trials
Guerbet
GuerbetFrance - Villepinte
1 program
DotaremN/A1 trial
Active Trials
NCT03023566Completed250Est. Nov 2017
Phenox
PhenoxGermany - Bochum
1 program
Mechanical Thrombectomy using the pRESET Thrombectomy deviceN/A1 trial
Active Trials
NCT03994822Completed340Est. May 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AbbottABT-888
Neurotech PharmaceuticalsIntracranial stent for wide-necked aneurysms
Neurotech PharmaceuticalsBridge
Neurotech PharmaceuticalsTubridge
Neurotech PharmaceuticalsIntracranial stent for wide-necked aneurysms
PhenoxMechanical Thrombectomy using the pRESET Thrombectomy device
GuerbetDotarem

Clinical Trials (7)

Total enrollment: 1,171 patients across 7 trials

NCT00649207AbbottABT-888

A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases

Start: Mar 2008Est. completion: Mar 201380 patients
Phase 1Completed
NCT06189950Neurotech PharmaceuticalsIntracranial stent for wide-necked aneurysms

Registration Trial of the Intracranial Visualized Stent for the Wide-necked Intracranial Aneurysms:REBRIDGE

Start: Oct 2023Est. completion: Oct 2026200 patients
N/ARecruiting
NCT06186024Neurotech PharmaceuticalsBridge

A PROSPECTIVE, MULTICENTER, SINGLE-ARM TRIAL FOR THE NEW SIZES OF BRIDGE STENTS FOR VERTEBRAL ARTERY STENOSIS: Bridge-MAX

Start: Sep 2023Est. completion: Jan 202536 patients
N/AUnknown
NCT05829746Neurotech PharmaceuticalsTubridge

PROSPECTIVE, MULTI-CENTER, OPEN-LABEL, SINGLE-ARM REGISTRATION TRIAL OF THE TUBRIDGE FOR THE TREATMENT OF WIDE-NECKED SMALL AND MEDIUM-SIZED INTRACRANIAL ANEURYSMS

Start: Nov 2022Est. completion: Dec 202465 patients
N/AUnknown
NCT05275296Neurotech PharmaceuticalsIntracranial stent for wide-necked aneurysms

Registration Trial of the Intracranial Visualized Stent for the Wide-necked Intracranial Aneurysms

Start: Jan 2022Est. completion: Dec 2023200 patients
N/AUnknown
NCT03994822PhenoxMechanical Thrombectomy using the pRESET Thrombectomy device

pRESET for Occlusive Stroke Treatment

Start: Oct 2019Est. completion: May 2022340 patients
N/ACompleted
NCT03023566GuerbetDotarem

Intra-individual Open-label, Single Center Study to Compare Unenhanced MRI With Dotarem Enhanced MRI

Start: Feb 2017Est. completion: Nov 2017250 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 1,171 patients
9 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.