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Brain Concussion

1
Pipeline Programs
10
Companies
9
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

9 companies ranked by most advanced pipeline stage

Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
2 programs
1
Virtual Neuromuscular/Dual-Task TrainingPhase 11 trial
Neuromuscular trainingN/A1 trial
Active Trials
NCT03917290Completed40Est. Apr 2022
NCT05594225Active Not Recruiting88Est. Sep 2025
Impact Therapeutics
Impact TherapeuticsChina - Shanghai
3 programs
ImPACT Online/Paper Pencil TestsN/A1 trial
ImPACT Online/Paper Pencil TestsN/A1 trial
Pen and paper neuropsychological testN/A1 trial
Active Trials
NCT03180905Unknown800Est. Dec 2024
NCT02701842Completed400Est. Sep 2016
NCT02597504Terminated1,600Est. Oct 2019
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
3D-MOT NeurotrackerN/A
MSD
MSDIreland - Ballydine
1 program
3D-MOT NeurotrackerN/A1 trial
Active Trials
NCT03213730Completed63Est. Aug 2019
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
3D-MOT NeurotrackerN/A
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
Balance and Mild Traumatic Brain Injury (TBI)N/A
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
Balance and Mild Traumatic Brain Injury (TBI)N/A1 trial
Active Trials
NCT01377454Completed47Est. Aug 2012
Oculogica
OculogicaWI - New Richmond
1 program
EyeBox CNSN/A1 trial
Active Trials
NCT02776462Completed321Est. Jun 2018
NeurOptics
NeurOpticsCA - Irvine
1 program
Pupillary AssessmentN/A1 trial
Active Trials
NCT04540445Unknown130Est. Dec 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Colorado TherapeuticsVirtual Neuromuscular/Dual-Task Training
NeurOpticsPupillary Assessment
Colorado TherapeuticsNeuromuscular training
Impact TherapeuticsImPACT Online/Paper Pencil Tests
MSD3D-MOT Neurotracker
OculogicaEyeBox CNS
Impact TherapeuticsImPACT Online/Paper Pencil Tests
Impact TherapeuticsPen and paper neuropsychological test
Human BioSciencesBalance and Mild Traumatic Brain Injury (TBI)

Clinical Trials (9)

Total enrollment: 3,489 patients across 9 trials

NCT05594225Colorado TherapeuticsVirtual Neuromuscular/Dual-Task Training

Tele-Rehabilitation to Improve Mild Traumatic Brain Injury Recovery and Reduce Subsequent Injury Risk

Start: Aug 2023Est. completion: Sep 202588 patients
Phase 1Active Not Recruiting
NCT04540445NeurOpticsPupillary Assessment

Utility of Pupillary Metrics in Diagnosis and Management of Concussion in Children

Start: Mar 2020Est. completion: Dec 2022130 patients
N/AUnknown
NCT03917290Colorado TherapeuticsNeuromuscular training

A Sports Injury Prevention Program to Reduce Subsequent Injuries After Concussion

Start: Apr 2019Est. completion: Apr 202240 patients
N/ACompleted
NCT03180905Impact TherapeuticsImPACT Online/Paper Pencil Tests

ImPACT Normative Extension

Start: May 2017Est. completion: Dec 2024800 patients
N/AUnknown
NCT03213730MSD3D-MOT Neurotracker

Perceptual-Cognitive Training After a Mild Traumatic Brain Injury: Towards a Sensitive Marker for Recovery

Start: Jan 2017Est. completion: Aug 201963 patients
N/ACompleted
NCT02776462OculogicaEyeBox CNS

Use of Eye Movement Tracking to Detect Oculomotor Abnormality in Traumatic Brain Injury Patients

Start: Jun 2016Est. completion: Jun 2018321 patients
N/ACompleted
NCT02701842Impact TherapeuticsImPACT Online/Paper Pencil Tests

ImPACT Online Clinical Study

Start: Feb 2016Est. completion: Sep 2016400 patients
N/ACompleted
NCT02597504Impact TherapeuticsPen and paper neuropsychological test

Development of a Neurocognitive Screening Test

Start: Oct 2015Est. completion: Oct 20191,600 patients
N/ATerminated
NCT01377454Human BioSciencesBalance and Mild Traumatic Brain Injury (TBI)

Balance and Mild Traumatic Brain Injury (TBI)

Start: Jun 2011Est. completion: Aug 201247 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

10 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.