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Bowel Preparation Before Colonoscopy

4
Pipeline Programs
2
Companies
3
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
2
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

POLYETHYLENE GLYCOL 3350Approved
polyethylene glycol
Unknown Company
Osmotic Laxative [EPC]oral2009

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Alfasigma
AlfasigmaItaly - Bologna
2 programs
1
1
polyethylene glycolPhase 41 trial
PMF104Phase 31 trial
Active Trials
NCT03106922Unknown430Est. Jul 2020
NCT04709770Unknown264Est. Mar 2022
Integrated Biosciences
Integrated BiosciencesCA - San Carlos
1 program
1
Picosulfate sodium, magnesium oxide, citric acidPhase 31 trial
Active Trials
NCT01984008Completed631Est. Jun 2014

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Alfasigmapolyethylene glycol
AlfasigmaPMF104
Integrated BiosciencesPicosulfate sodium, magnesium oxide, citric acid

Clinical Trials (3)

Total enrollment: 1,325 patients across 3 trials

NCT04709770Alfasigmapolyethylene glycol

Low-volume vs High-volume Polyethylene Glycol Based Bowel Preparation for Colonoscopy in People Receiving Hemodialysis

Start: Feb 2021Est. completion: Mar 2022264 patients
Phase 4Unknown

A Trial to Evaluate the Efficacy and Safety of PMF104 Compared to a Conventional PEG-electrolyte Solution in Children

Start: Apr 2016Est. completion: Jul 2020430 patients
Phase 3Unknown
NCT01984008Integrated BiosciencesPicosulfate sodium, magnesium oxide, citric acid

A Study of the Efficacy and Safety of Bowklean and Klean-Prep With Dulcolax for the Bowel Preparation Prior Colonoscopy

Start: Oct 2013Est. completion: Jun 2014631 patients
Phase 3Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.