Blood Pressure

3
Pipeline Programs
5
Companies
5
Clinical Trials
2
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
2
Early DiscoveryClinical DevelopmentMarket

On Market (2)

Approved therapies currently available

U
PHENYLEPHRINE HYDROCHLORIDEApproved
phenylephrine hydrochloride
Unknown Company
intravenous2025
U
VAZCULEPApproved
phenylephrine hydrochloride
Unknown Company
intravenous2014

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Bayer
BayerLEVERKUSEN, Germany
1 program
1
Phenylephrine HydrochloridePhase 31 trial
Active Trials
NCT00874120Completed116Est. Feb 2009
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
EtomidateN/A1 trial
Active Trials
NCT04865614Completed57Est. Dec 2020
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
Evaluation of Target Organs Impairment on Patients Suffering From High Blood PressureN/A1 trial
Active Trials
NCT00925470Completed1,200Est. Dec 2009
Zoll
ZollCA - San Jose
1 program
Intra-Shift NappingN/A1 trial
Active Trials
NCT04469803CompletedEst. Oct 2022
Bracco
BraccoItaly - Milan
1 program
Low-Sodium Salt SubstituteN/A1 trial
Active Trials
NCT05425030CompletedEst. Dec 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
BayerPhenylephrine Hydrochloride
BraccoLow-Sodium Salt Substitute
ZollIntra-Shift Napping
Heidelberg PharmaEtomidate
AstraZenecaEvaluation of Target Organs Impairment on Patients Suffering From High Blood Pressure

Clinical Trials (5)

Total enrollment: 1,373 patients across 5 trials

NCT00874120BayerPhenylephrine Hydrochloride

Safety Study Comparing Phenylephrine HCL Extended Release Tablets 30 mg and Placebo (Study CL2007-07)(P07529)(COMPLETED)

Start: Dec 2008Est. completion: Feb 2009116 patients
Phase 3Completed
NCT05425030BraccoLow-Sodium Salt Substitute

A Community Health Worker-Led LSSS Intervention in Bangladesh

Start: Jan 2023Est. completion: Dec 2024
N/ACompleted
NCT04469803ZollIntra-Shift Napping

Impact of Intra-Shift Napping on EMS Cardiovascular Health

Start: Mar 2021Est. completion: Oct 2022
N/ACompleted
NCT04865614Heidelberg PharmaEtomidate

Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair

Start: Apr 2019Est. completion: Dec 202057 patients
N/ACompleted
NCT00925470AstraZenecaEvaluation of Target Organs Impairment on Patients Suffering From High Blood Pressure

Evaluation of Target Organs Impairment on Patients Suffering From High Blood Pressure

Start: Jun 2009Est. completion: Dec 20091,200 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
5 companies competing in this space