Bacteremia

3
Pipeline Programs
5
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
1 program
1
Cefazolin IVPhase 31 trial
Active Trials
NCT00108433Terminated61Est. Sep 2006
BP
Basilea PharmaceuticaSwitzerland - Allschwil
1 program
1
ceftobiprole medocarilPhase 21 trial
Active Trials
NCT00505258WithdrawnEst. Apr 2009
Armata Pharmaceuticals
Armata PharmaceuticalsLOS ANGELES, CA
1 program
1
AP-SA02Phase 1/21 trial
Active Trials
NCT05184764Completed50Est. Jan 2025
ExThera Medical
ExThera MedicalCA - Martinez
1 program
Seraph 100 FilterN/A1 trial
Active Trials
NCT02914132Completed15Est. Jun 2018

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
PfizerCefazolin IV
Basilea Pharmaceuticaceftobiprole medocaril
Armata PharmaceuticalsAP-SA02
ExThera MedicalSeraph 100 Filter

Clinical Trials (4)

Total enrollment: 126 patients across 4 trials

NCT00108433PfizerCefazolin IV

Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections

Start: Sep 2005Est. completion: Sep 200661 patients
Phase 3Terminated
NCT00505258Basilea Pharmaceuticaceftobiprole medocaril

Ceftobiprole in the Treatment of Hospitalized Patients With Staphylococcus Aureus Bacteremia

Est. completion: Apr 2009
Phase 2Withdrawn

Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia

Start: Apr 2022Est. completion: Jan 202550 patients
Phase 1/2Completed

Safety Evaluation of Seraph® 100 to Reduce Bacteremia in Patients on Hemodialysis

Start: Feb 2016Est. completion: Jun 201815 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
5 companies competing in this space