B-cell Malignancy

3
Pipeline Programs
2
Companies
3
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
3
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

BeOne Medicines
BeOne MedicinesCA - San Carlos
2 programs
2
BGB-16673Phase 1/21 trial
BGB-16673Phase 1/21 trial
Active Trials
NCT06634589Recruiting80Est. Dec 2029
NCT05006716Recruiting614Est. Nov 2029
CRISPR Therapeutics
1 program
1
CTX110Phase 1/21 trial
Active Trials
NCT04035434Terminated93Est. Oct 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
BeOne MedicinesBGB-16673
BeOne MedicinesBGB-16673
CRISPR TherapeuticsCTX110

Clinical Trials (3)

Total enrollment: 787 patients across 3 trials

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Start: Nov 2024Est. completion: Dec 202980 patients
Phase 1/2Recruiting

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

Start: Sep 2021Est. completion: Nov 2029614 patients
Phase 1/2Recruiting

A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON)

Start: Jul 2019Est. completion: Oct 202493 patients
Phase 1/2Terminated

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 787 patients
2 companies competing in this space