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Avascular Necrosis

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Pipeline Programs
2
Companies
7
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Zimmer Biomet
Zimmer BiometFL - Jacksonville
6 programs
AS Domelock SystemN/A1 trial
Allofit® IT With HXPE in Total Hip ArthroplastyN/A1 trial
Avascular Necrosis (AVN) Long-Term Follow-upN/A1 trial
Continuum Metal on Polyethylene Acetabular SystemN/A1 trial
Metal-on-Metal ArticulationN/A1 trial
+1 more programs
Active Trials
NCT03312465Active Not Recruiting73Est. Dec 2032
NCT03672929Completed197Est. Jul 2025
NCT00833430Terminated35Est. Feb 2013
+3 more trials
Biocomposites
BiocompositesChina - Shanghai
1 program
Genex with ABMCN/A1 trial
Active Trials
NCT05706909Active Not Recruiting22Est. Jul 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
BiocompositesGenex with ABMC
Zimmer BiometAS Domelock System
Zimmer Biomettotal knee arthroplasty
Zimmer BiometAllofit® IT With HXPE in Total Hip Arthroplasty
Zimmer BiometContinuum Metal on Polyethylene Acetabular System
Zimmer BiometMetal-on-Metal Articulation
Zimmer BiometAvascular Necrosis (AVN) Long-Term Follow-up

Clinical Trials (7)

Total enrollment: 647 patients across 7 trials

The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head

Start: Feb 2023Est. completion: Jul 202722 patients
N/AActive Not Recruiting
NCT03312465Zimmer BiometAS Domelock System

Anatomical Shoulder Domelock System Study

Start: Sep 2017Est. completion: Dec 203273 patients
N/AActive Not Recruiting
NCT03111407Zimmer Biomettotal knee arthroplasty

iAssist vs. Conventional Instrumentation in Total Knee Arthroplasty

Start: Apr 2014Est. completion: Dec 201872 patients
N/ACompleted
NCT03672929Zimmer BiometAllofit® IT With HXPE in Total Hip Arthroplasty

Allofit® IT With HXPE in Total Hip Arthroplasty

Start: Jun 2011Est. completion: Jul 2025197 patients
N/ACompleted
NCT01307384Zimmer BiometContinuum Metal on Polyethylene Acetabular System

Zimmer Continuum Metal on Polyethylene (MoP) PostMarket Clinical Followup (PMCF) Study

Start: Mar 2011Est. completion: Dec 2027165 patients
N/AActive Not Recruiting
NCT03382652Zimmer BiometMetal-on-Metal Articulation

Continuum™ Metal Bearing System in Total Hip Arthroplasty

Start: Feb 2011Est. completion: Oct 202283 patients
N/ACompleted
NCT00833430Zimmer BiometAvascular Necrosis (AVN) Long-Term Follow-up

Avascular Necrosis (AVN) Long-Term Follow-up

Start: Jun 2006Est. completion: Feb 201335 patients
N/ATerminated

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.