Attention-Deficit/Hyperactivity Disorder (ADHD)

5
Pipeline Programs
4
Companies
6
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
1
0
3
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

U
GUANFACINE HYDROCHLORIDEApproved
guanfacine
Unknown Company
oral2023

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Eli Lilly and Company
Eli Lilly and CompanyINDIANAPOLIS, IN
2 programs
1
atomoxetinePhase 43 trials
Evaluating Clinical Outcomes of Treatment Effectiveness for Children and Adults With ADHDN/A
Active Trials
NCT00529893Completed30Est. Jun 2008
NCT00252278Unknown36
NCT00176436Completed40Est. Mar 2008
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
1
GuanfacinePhase 41 trial
Active Trials
NCT07300956Not Yet RecruitingEst. Jul 2030
N
NeurocentriaCA - Walnut Creek
1 program
1
NRCT-101SRPhase 2/31 trial
Active Trials
NCT06215144TerminatedEst. Nov 2025
M&
Merck & Co.RAHWAY, NJ
1 program
1
MK0249Phase 21 trial
Active Trials
NCT00475735Completed72Est. Apr 2008

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
City TherapeuticsGuanfacine
Eli Lilly and Companyatomoxetine
Eli Lilly and Companyatomoxetine
NeurocentriaNRCT-101SR
Merck & Co.MK0249
Eli Lilly and Companyatomoxetine

Clinical Trials (6)

Total enrollment: 178 patients across 6 trials

Treating Young Children With Attention Deficit Hyperactivity Disorder

Start: Feb 2026Est. completion: Jul 2030
Phase 4Not Yet Recruiting

Effect of Atomoxetine on ADHD-Related Insomnia in Children and Adolescents

Start: Nov 200536 patients
Phase 4Unknown

Atomoxetine for Treatment of Weight Gain in Olanzapine or Clozapine Patients

Start: Feb 2004Est. completion: Mar 200840 patients
Phase 4Completed

Study to Evaluate NRCT-101SR in Pediatric Subjects With ADHD

Start: Jan 2024Est. completion: Nov 2025
Phase 2/3Terminated

A Study to Test the Safety and Efficacy of MK0249 in Patients With ADHD (0249-018)(COMPLETED)

Start: Jul 2007Est. completion: Apr 200872 patients
Phase 2Completed

Efficacy of Atomoxetine in the Neuropsychological Tests Among Children With ADHD

Start: Jul 2007Est. completion: Jun 200830 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 companies competing in this space