Attention Deficit Disorder With Hyperactivity

5
Pipeline Programs
4
Companies
8
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
1
2
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Takeda
TakedaTOKYO, Japan
1 program
1
SPD503Phase 34 trials
Active Trials
NCT01500694Completed215Est. Sep 2015
NCT00919867Completed42Est. Jul 2009
NCT00901576Completed38Est. Jul 2009
+1 more trials
Eli Lilly and Company
Eli Lilly and CompanyINDIANAPOLIS, IN
1 program
1
atomoxetinePhase 31 trial
Active Trials
NCT00386581Completed105Est. Feb 2005
Avalo Therapeutics
2 programs
1
1
NFC-1Phase 2/31 trial
NFC-1 100 mgPhase 11 trial
Active Trials
NCT03006367CompletedEst. Mar 2017
NCT02777931CompletedEst. Feb 2017
Pfizer
PfizerNEW YORK, NY
1 program
1
AtomoxetinePhase 21 trial
Active Trials
NCT00174226Completed241Est. Jan 2006

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
TakedaSPD503
Eli Lilly and Companyatomoxetine
TakedaSPD503
Avalo TherapeuticsNFC-1
PfizerAtomoxetine
Avalo TherapeuticsNFC-1 100 mg
TakedaSPD503
TakedaSPD503

Clinical Trials (8)

Total enrollment: 986 patients across 8 trials

Access to Extended Release Guanfacine HCl for Subjects Who Participated in Studies SPD503-315 or SPD503-316 in Europe

Start: Mar 2012Est. completion: Sep 2015215 patients
Phase 3Completed

Efficacy, Tolerability, and Safety of Once-Daily Atomoxetine Hydrochloride Versus Placebo in Russian Children and Adolescents With Attention-Deficit/Hyperactivity Disorder

Start: Jul 2004Est. completion: Feb 2005105 patients
Phase 3Completed

Safety and Efficacy of SPD503 in Treating Attention-Deficit/Hyperactivity Disorder (ADHD) in Children Aged 6-17

Start: Jan 2003Est. completion: Aug 2003345 patients
Phase 3Completed

Efficacy and Safety of NFC-1 in Adolescents With Genetic Disorders Impacting mGluR and ADHD

Start: Jun 2016Est. completion: Feb 2017
Phase 2/3Completed

Treatment of Adult ADHD With Atomoxetine or Atomoxetine and Buspar

Start: Nov 2004Est. completion: Jan 2006241 patients
Phase 2Completed

Pharmacokinetic and Tolerability Study of NFC-1 in Subjects Aged 6-17 Years With ADHD

Start: Jan 2017Est. completion: Mar 2017
Phase 1Completed

A Drug Interaction Study of SPD503 and Vyvanse Administered Alone and In Combination in Normal Healthy Volunteers

Start: Jun 2009Est. completion: Jul 200942 patients
Phase 1Completed

A Drug Interaction Study of SPD503 and Concerta Administered Alone and In Combination in Normal Healthy Volunteers

Start: May 2009Est. completion: Jul 200938 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs — potential near-term approvals
4 companies competing in this space