Astigmatism

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Pipeline Programs
5
Companies
23
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Alcon
AlconFORT WORTH, TX
8 programs
Clareon Vivity Extended Vision IOLN/A1 trial
Corneal Astigmatism Measurement StudyN/A1 trial
Delefilcon A toric soft contact lensN/A1 trial
Lotrafilcon B contact lensN/A1 trial
Lotrafilcon B toric contact lenses with HYDRAGLYDEN/A1 trial
+3 more programs
Active Trials
NCT06784063CompletedEst. Jun 2025
NCT00818532Completed50Est. Apr 2009
NCT05805345WithdrawnEst. May 2023
+5 more trials
Bausch + Lomb
Bausch + LombNJ - Bridgewater
7 programs
ControlN/A1 trial
Evaluation of the Bausch & Lomb PureVision Under Nighttime Driving ConditionsN/A1 trial
Kalifilcon Toric LensN/A1 trial
REVIVE samfilcon B custom toric contact lensesN/A1 trial
enVista® One-Piece Hydrophobic Acrylic Toric IOLN/A1 trial
+2 more programs
Active Trials
NCT03681808Completed242Est. Dec 2019
NCT00581659Completed40Est. Oct 2008
NCT06098937Completed30Est. Sep 2023
+4 more trials
J&
Johnson & JohnsonNEW BRUNSWICK, NJ
6 programs
Etafilcon A toric contact lensN/A1 trial
Investigational daily disposable, soft, toric lenses manufactured on 4th Generation TechnologyN/A1 trial
senofilcon AN/A1 trial
senofilcon AN/A1 trial
senofilcon A toricN/A1 trial
+1 more programs
Active Trials
NCT01055132Completed70Est. Feb 2010
NCT06967129Completed281Est. Jul 2025
NCT01579045Completed24Est. Mar 2013
+3 more trials
Abbott
AbbottABBOTT PARK, IL
1 program
LASIKN/A1 trial
Active Trials
NCT01675492Completed126Est. Nov 2016
Novartis
NovartisBASEL, Switzerland
1 program
Verion-LenSxN/A1 trial
Active Trials
NCT02763124Completed18Est. Oct 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Bausch + LombREVIVE samfilcon B custom toric contact lenses
Johnson & JohnsonInvestigational daily disposable, soft, toric lenses manufactured on 4th Generation Technology
AlconClareon Vivity Extended Vision IOL
Bausch + LombKalifilcon Toric Lens
Bausch + Lombkalifilcon A Daily Disposable Toric
AlconDelefilcon A toric soft contact lens
AlconVerofilcon A toric soft contact lenses
Bausch + Lombkalifilcon A Daily Disposable Toric LD213001 Contact Lenses
Alconverofilcon A toric contact lenses
Bausch + LombControl
AlconLotrafilcon B toric contact lenses with HYDRAGLYDE
NovartisVerion-LenSx
Bausch + LombenVista® One-Piece Hydrophobic Acrylic Toric IOL
AbbottLASIK
Johnson & Johnsonsenofilcon A

Showing 15 of 23 trials with date data

Clinical Trials (23)

Total enrollment: 1,563 patients across 23 trials

NCT06785194Bausch + LombREVIVE samfilcon B custom toric contact lenses

Revive Toric RWE Study

Start: May 2026Est. completion: Jul 202630 patients
N/ANot Yet Recruiting
NCT06967129Johnson & JohnsonInvestigational daily disposable, soft, toric lenses manufactured on 4th Generation Technology

Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process

Start: Apr 2025Est. completion: Jul 2025281 patients
N/ACompleted
NCT06784063AlconClareon Vivity Extended Vision IOL

Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)

Start: Apr 2025Est. completion: Jun 2025
N/ACompleted
NCT06098937Bausch + LombKalifilcon Toric Lens

Kalifilcon A Toric Compared to Commercially Available Lenses

Start: Sep 2023Est. completion: Sep 202330 patients
N/ACompleted
NCT06069609Bausch + Lombkalifilcon A Daily Disposable Toric

Orientation Characteristics of Daily Disposable Toric Contact Lenses

Start: Aug 2023Est. completion: Aug 202330 patients
N/ACompleted
NCT05805345AlconDelefilcon A toric soft contact lens

Clinical Comparison of Toric Contact Lenses Fit Characteristics

Start: Apr 2023Est. completion: May 2023
N/AWithdrawn
NCT05483127AlconVerofilcon A toric soft contact lenses

Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses

Start: Sep 2022Est. completion: Oct 2022153 patients
N/ACompleted
NCT05129124Bausch + Lombkalifilcon A Daily Disposable Toric LD213001 Contact Lenses

Insertion Clinical Study to Evaluate the Orientation Characteristics of Multiple Kalifilcon A Daily Disposable Toric LD213001 Contact Lenses

Start: Nov 2021Est. completion: Jan 202230 patients
N/ACompleted
NCT04464044Alconverofilcon A toric contact lenses

Clinical Performance of a Daily Disposable Toric Silicone Hydrogel Contact Lens

Start: Jul 2020Est. completion: Aug 2020
N/ACompleted
NCT03681808Bausch + LombControl

Evaluate the Safety and Effectiveness of the Biotrue ONEday for Astigmatism

Start: Oct 2018Est. completion: Dec 2019242 patients
N/ACompleted
NCT03392532AlconLotrafilcon B toric contact lenses with HYDRAGLYDE

Comparison of Two Silicone Hydrogel Toric Contact Lenses

Start: Jan 2018Est. completion: Jan 2018
N/ACompleted
NCT02763124NovartisVerion-LenSx

Pseudophakic Astigmatic Reduction With Verion-LenSx Arcuate Incisions

Start: May 2016Est. completion: Oct 201618 patients
N/ACompleted
NCT01852084Bausch + LombenVista® One-Piece Hydrophobic Acrylic Toric IOL

Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism

Start: Mar 2013Est. completion: Dec 2016191 patients
N/ACompleted
NCT01675492AbbottLASIK

Safety and Effectiveness of Wavefront-guided LASIK for the Correction of Mixed Astigmatism

Start: Dec 2012Est. completion: Nov 2016126 patients
N/ACompleted
NCT01579045Johnson & Johnsonsenofilcon A

Effect of Head and Gaze Position on Soft Toric Contact Lens Performance

Start: Aug 2012Est. completion: Mar 201324 patients
N/ACompleted
NCT01207466AlconNelfilcon A investigational contact lens

Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism

Start: Sep 2010Est. completion: Oct 2010
N/ACompleted
NCT01055132Johnson & JohnsonEtafilcon A toric contact lens

Dispensing Evaluation of New Daily Disposable Toric Soft Contact Lens.

Start: Jan 2010Est. completion: Feb 201070 patients
N/ACompleted
NCT01007812AlconLotrafilcon B contact lens

Clinical Comparison of Two Silicone Hydrogel Toric Lenses in the US

Start: Oct 2009Est. completion: Nov 2009
N/ACompleted
NCT00818532AlconCorneal Astigmatism Measurement Study

Corneal Astigmatism Measurement Study

Start: Dec 2008Est. completion: Apr 200950 patients
N/ACompleted
NCT00581659Bausch + LombEvaluation of the Bausch & Lomb PureVision Under Nighttime Driving Conditions

Evaluation of the Bausch & Lomb PureVision Under Nighttime Driving Conditions

Start: Nov 2007Est. completion: Oct 200840 patients
N/ACompleted
NCT00584831Johnson & Johnsonsenofilcon A

Effect of Eye Movement on Toric Lens Orientation and Visual Acuity

Start: Oct 2007Est. completion: Feb 200840 patients
N/ACompleted
NCT00584220Johnson & Johnsonsenofilcon A toric

Evaluation of Two Toric Soft Contact Lenses After Two Weeks of Wear

Start: Sep 2007Est. completion: Dec 200796 patients
N/ACompleted
NCT00762502Johnson & Johnsonsenofilcon A toric contact lens

Comparison of Senofilcon A Toric Lenses to Balafilcon A Toric Lenses Over Extended Wear Period

Start: Jun 2007Est. completion: Jan 2008112 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

5 companies competing in this space