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Arterial Occlusive Diseases

2
Pipeline Programs
6
Companies
12
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

UNION therapeutics
UNION therapeuticsDenmark - Hellerup
2 programs
1
stentPhase 42 trials
dyna-pbvN/A1 trial
Active Trials
NCT03248323Unknown120Est. Jun 2019
NCT07521124Not Yet Recruiting104Est. Jun 2029
NCT01147419Unknown200Est. Jun 2015
iNova Pharmaceuticals
iNova PharmaceuticalsAustralia - Chatswood
1 program
1
PZ-128Phase 21 trial
Active Trials
NCT02561000Completed100Est. Sep 2019
Cordis
CordisFL - Miami Lakes
3 programs
Smart StentPHASE_41 trial
stentPHASE_41 trial
stentPHASE_41 trial
Active Trials
NCT00235131Completed200Est. May 2009
NCT00289055Terminated10Est. Jun 2008
NCT00232843Completed150Est. May 2009
Medtronic
MedtronicNJ - Phillipsburg
2 programs
MDT-4107 Drug Eluting StentN/A1 trial
MDT-4107 Zotarolimus-Eluting Coronary StentN/A1 trial
Active Trials
NCT00927940Completed100Est. Feb 2015
NCT01150500Completed65Est. Jun 2016
Boston Scientific
Boston ScientificCA - Valencia
2 programs
Peripheral stentingN/A1 trial
Peripheral stentingN/A1 trial
Active Trials
NCT02921230Completed775Est. Nov 2023
NCT03037411Completed291Est. Mar 2022
Grifols
GrifolsNEW YORK, NY
1 program
PlasminPHASE_11 trial
Active Trials
NCT00418483Completed83Est. Apr 2010

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
UNION therapeuticsstent
Cordisstent
CordisSmart Stent
Cordisstent
iNova PharmaceuticalsPZ-128
GrifolsPlasmin
UNION therapeuticsstent
Boston ScientificPeripheral stenting
Boston ScientificPeripheral stenting
UNION therapeuticsdyna-pbv
MedtronicMDT-4107 Zotarolimus-Eluting Coronary Stent
MedtronicMDT-4107 Drug Eluting Stent

Clinical Trials (12)

Total enrollment: 2,198 patients across 12 trials

Comparison of Stent and Prothesis Bypass in Superficial Femoral Artery

Start: Jun 2010Est. completion: Jun 2015200 patients
Phase 4Unknown

The Study to Compare the Treatment of Angioplasty and Stents in SFA Occlusions.

Start: Nov 2005Est. completion: Jun 200810 patients
Phase 4Terminated

The Study to Compare the Cordis SMART™ Stent System With the Bard® Luminexx™ Stent

Start: May 2005Est. completion: May 2009200 patients
Phase 4Completed

The Study to Treat Superficial Femoral Artery Occlusions.

Start: Mar 2005Est. completion: May 2009150 patients
Phase 4Completed

Safety of PZ-128 in Subjects Undergoing Non-Emergent Percutaneous Coronary Intervention

Start: May 2016Est. completion: Sep 2019100 patients
Phase 2Completed

A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft Occlusion

Start: Mar 2007Est. completion: Apr 201083 patients
Phase 1Completed

ABC Maintenance Therapy for AML

Start: Jun 2026Est. completion: Jun 2029104 patients
N/ANot Yet Recruiting
NCT03037411Boston ScientificPeripheral stenting

A Real World Evaluation of the ELUVIA Stent in Subjects With Lesions Located in the Femoropopliteal Arteries

Start: Dec 2016Est. completion: Mar 2022291 patients
N/ACompleted
NCT02921230Boston ScientificPeripheral stenting

Trial Comparing ELUVIA Versus Bare Metal Stent in Treatment of Superficial Femoral and/or Proximal Popliteal Artery

Start: Oct 2016Est. completion: Nov 2023775 patients
N/ACompleted

A Prospective Study: the Value of Using iFlow and PBV in the Endovascular Treatment of Infrapopliteal Arterial Occlusive Diseases

Start: Jun 2016Est. completion: Jun 2019120 patients
N/AUnknown
NCT01150500MedtronicMDT-4107 Zotarolimus-Eluting Coronary Stent

RESOLUTE Japan SVS: The Clinical Evaluation of the MDT-4107 DES in the Treatment of De Novo Lesions in Small Diameter Native Coronary Arteries

Start: Jun 2010Est. completion: Jun 201665 patients
N/ACompleted
NCT00927940MedtronicMDT-4107 Drug Eluting Stent

RESOLUTE Japan - The Clinical Evaluation of the MDT-4107 Drug-Eluting Coronary Stent

Start: Mar 2009Est. completion: Feb 2015100 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.