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Anterior Cruciate Ligament Reconstruction

2
Pipeline Programs
7
Companies
6
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Biocorp
BiocorpFrance - Issoire
2 programs
2
KneehabPhase 31 trial
KneehabPhase 31 trial
Active Trials
NCT00738010Completed131Est. Oct 2006
NCT00737750Completed131Est. Oct 2006
Nordic Pharma
Nordic PharmaFrance - Paris
1 program
Adjustable versus fixed suspensory loop femoral side graft fixationN/A1 trial
Active Trials
NCT03184922Active Not Recruiting165Est. Jan 2026
Stryker
StrykerCA - San Jose
1 program
Adjustable versus fixed suspensory loop femoral side graft fixationN/A
Linnaeus Therapeutics
Linnaeus TherapeuticsNJ - Haddonfield
1 program
Novel programN/A1 trial
Active Trials
NCT06318039Not Yet Recruiting100Est. Oct 2027
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
telerehabilitationN/A1 trial
Active Trials
NCT06327555Completed164Est. Jul 2025
Revalesio
RevalesioWA - Tacoma
1 program
RNS60PHASE_21 trial
Active Trials
NCT01922427Withdrawn0

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
BiocorpKneehab
BiocorpKneehab
Linnaeus TherapeuticsNovel program
UNION therapeuticstelerehabilitation
Nordic PharmaAdjustable versus fixed suspensory loop femoral side graft fixation

Clinical Trials (6)

Total enrollment: 691 patients across 6 trials

NCT00738010BiocorpKneehab

Effectiveness of Kneehab in Strengthening Quadriceps in Rehabilitation Post Anterior Cruciate Ligament (ACL) Reconstruction

Start: Apr 2005Est. completion: Oct 2006131 patients
Phase 3Completed
NCT00737750BiocorpKneehab

Effectiveness of Kneehab in Strengthening the Quadriceps of Patients Post Anterior Cruciate Ligament (ACL) Reconstruction

Start: Apr 2005Est. completion: Oct 2006131 patients
Phase 3Completed
NCT01922427RevalesioRNS60

Study of RNS60 on Pain and Function After Knee Anterior Cruciate Ligament Surgery

0
Phase 2Withdrawn
NCT06318039Linnaeus TherapeuticsNovel program

Operation ACL: Rehabilitation After Anterior Cruciate Ligament Reconstruction

Start: Oct 2024Est. completion: Oct 2027100 patients
N/ANot Yet Recruiting
NCT06327555UNION therapeuticstelerehabilitation

Comparison of the Efficacy of Telerehabilitation and In-person Rehabilitation Based on Wearable Devices After ACLR Surgery: a Multicenter Randomized Controlled Trial

Start: Mar 2024Est. completion: Jul 2025164 patients
N/ACompleted
NCT03184922Nordic PharmaAdjustable versus fixed suspensory loop femoral side graft fixation

Fixed Versus Adjustable Loop in ACL Reconstruction

Start: Jul 2017Est. completion: Jan 2026165 patients
N/AActive Not Recruiting

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.