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Angioedema

2
Pipeline Programs
3
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
1
1
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 3 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Prothya Biosolutions
Prothya BiosolutionsBelgium - Brussels
2 programs
1
1
C1 inhibitor concentratePhase 31 trial
C1 inhibitor concentratePhase 2/31 trial
Active Trials
NCT00125541Completed6Est. May 2008
NCT00125151Completed15Est. Apr 2007
Rare Disease Therapeutics
1 program
VenipunctureN/A
Takeda
TakedaTOKYO, Japan
1 program
LanadelumabPHASE_3Monoclonal Antibody5 trials
Active Trials
NCT04583007No Longer Available
NCT05397431Active Not Recruiting155Est. Jun 2026
NCT05147181Completed48Est. Nov 2025
+2 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
TakedaLanadelumab
TakedaLanadelumab

Clinical Trials (2)

Total enrollment: 85 patients across 2 trials

Expanded Access Program With Lanadelumab for Japanese People With Hereditary Angioedema

Start: Feb 2021Est. completion: Jun 202212 patients
Phase 3Completed

A Study of Long-Term Safety and Efficacy of Lanadelumab for Prevention of Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor

Start: Feb 2021Est. completion: May 202373 patients
Phase 3Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.