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Anal Intraepithelial Neoplasia

4
Pipeline Programs
6
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
3
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
1100%
+ 5 programs with unclassified modality

Competitive Landscape

6 companies ranked by most advanced pipeline stage

MSD
MSDIreland - Ballydine
1 program
1
9-valent HPV vaccinationPhase 2
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
9-valent HPV vaccinationPhase 21 trial
Active Trials
NCT03947775Unknown228Est. May 2026
Inovio Pharmaceuticals
1 program
1
ElectroporationPhase 21 trial
Active Trials
NCT03603808Completed44Est. Jun 2025
ISA Pharmaceuticals
ISA PharmaceuticalsNetherlands - Oegstgeest
1 program
1
HPV-16 vaccinePhase 1/2Vaccine1 trial
Active Trials
NCT01923116Completed40Est. Dec 2017
Finch Therapeutics
1 program
Physical examinationN/A1 trial
Active Trials
NCT05858021Unknown30Est. Jul 2025
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
9-valent HPV vaccinationPHASE_2

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Sharp Therapeutics9-valent HPV vaccination
Inovio PharmaceuticalsElectroporation
ISA PharmaceuticalsHPV-16 vaccine
Finch TherapeuticsPhysical examination

Clinical Trials (4)

Total enrollment: 342 patients across 4 trials

NCT03947775Sharp Therapeutics9-valent HPV vaccination

HPV-SAVE_Merck_Sub-Study for Preventing Recurrence of HSIL

Start: Sep 2022Est. completion: May 2026228 patients
Phase 2Unknown

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Start: Sep 2018Est. completion: Jun 202544 patients
Phase 2Completed

Therapeutic HPV-16 Vaccination for the Treatment of Anal Dysplasia

Start: Aug 2013Est. completion: Dec 201740 patients
Phase 1/2Completed
NCT05858021Finch TherapeuticsPhysical examination

COrSIcA: Disease Measurement

Start: Jul 2023Est. completion: Jul 202530 patients
N/AUnknown

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.